The 6 best medicines for high blood pressure

Review of the best according to the editorial board. On the selection criteria. This material is subjective and does not constitute advertising and does not serve as a purchase guide. Before buying, you need to consult with a specialist.

Hypertension is so common among middle-aged and elderly people that many people perceive it as common and normal. But it is high blood pressure that most often leads to vascular catastrophes, mortality from which is in first place in the world population. Arterial hypertension and atherosclerosis are the cause of heart attacks and strokes, death and disability.

The rating of drugs includes drugs of various pharmacological groups, but all of them are united by the ability to fight high blood pressure. Readers should be warned against self-medication and attempts to purchase these drugs without a doctor's prescription. The popularity of drugs does not at all mean their safety and the possibility of uncontrolled use. These are serious drugs that can interact with other drugs, have various side effects, in case of an overdose, they can sharply lower blood pressure, and sometimes a thorough examination by a cardiologist is necessary for their appointment.

Rating of medicines for high blood pressure

Nomination	a place	Name of product	price
Rating of medicines for high blood pressure	1	Lozap (Losartan)	606 RUB
	2	Captopril	40 RUB.
	3	Arifon-retard (indapamide)	365 RUB
	4	Amlodipine (Norvasc)	332 RUB
	5	Prestarium (perindopril)	534 RUB
	6	Veroshpiron (spironolactone)	281 r

Lozap (Losartan)

Rating: 4.9

Drugs from the sartan group occupy a leading place in the market of drugs that protect against arterial hypertension. This medication does not affect the heart or blood vessels. The effect of all sartans is that they make vascular receptors insensitive to angiotensin, which is the final link in the conversion cascade that causes vasoconstriction. When taking losartan, blood pressure decreases immediately, already in the first hours.

Available in three dosages, 12.5 mg, 50 and 100. Indications for admission are hypertension, chronic heart failure with edema and shortness of breath, as well as the prevention of heart attack and hypertension. Apply Lozap, regardless of food intake, once. At the beginning of therapy, the dosage is 50 mg per day. The most pronounced effect develops a month after the start of taking the drug. Also, this drug can be used in patients with diabetic kidney damage. Lozap is produced by the Czech company Zentiva, and a monthly package consisting of 30 tablets of a standard dosage of 50 mg can be purchased for 235 rubles.

Advantages and disadvantages

The positive properties of this drug include good tolerance and the rare development of side effects, of which headache, dry nose or the development of weakness are more common. In the event that patients have impaired liver and kidney function, then special consultation with a specialist is required to adjust the dose. Also considered a plus is the ability to prescribe Lozap with other drugs to reduce blood pressure, but each case must be prescribed by the attending physician.

Captopril

Rating: 4.8

Perhaps, Captopril is the most common drug, and it belongs to the blockers of enzymes that catalyze the conversion of angiotensin, which ultimately constricts blood vessels and increases blood pressure. Captopril can fight heart failure, kidney damage in diabetes, and prevent recurrent episodes of myocardial infarction. The drug is prescribed in dosages of 25 and 50 mg according to the scheme prescribed by the doctor. Captopril is extremely popular with dozens of different dosage forms, of which the most affordable are extremely low cost. So, a domestic drug produced by Ozone LLC costs 10 rubles. per pack of 40 tablets of 25 mg.

Advantages and disadvantages

Captopril The good thing is that it is able to quickly lower blood pressure during a hypertensive crisis, and thereby protect against heart attack and stroke, which it earned a place in this ranking. When you take the sublingual of one tablet, the pressure drops in literally a matter of minutes. The positive qualities include the low cost of the drug. Captopril can also have various contraindications and restrictions for use that only a doctor can assess, for example, bilateral narrowing of the renal arteries. It is undesirable to use it for long-term therapy, since it can drastically reduce blood pressure, which can provoke cerebrovascular accident in the elderly.

Arifon-retard (indapamide)

Rating: 4.8

This drug is a diuretic that removes excess fluid from the body, while the drug lowers blood pressure. In addition, indapamide improves the tone of the arterial walls, and reduces the excessive development of the heart muscle (myocardial hypertrophy). The drug is usually taken one tablet (1.5 mg) per day, in the morning. The most popular commercial name for the original indapamide, which first appeared on the market, is Arifon retard (sustained release of the drug). The medicine is produced by the French company Servier, oval-shaped tablets provide a sustained release of the substance, which allows it to be used, unlike ordinary indapamide, once a day. A package of the drug, calculated for a month, will cost 300 rubles.

Advantages and disadvantages

The advantages of the drug include the effect on the formation of urine in small doses – it is not a diuretic in fact, only by belonging to a group, a single use, a good effect of stabilizing blood pressure. That is why you should not take Arifon retard to reduce puffiness, but should only be taken with the aim of lowering blood pressure. This drug was also included in the rating due to its good tolerability in various groups of patients, and in connection with the possibility of taking it in old age in patients with diabetes and increased body weight. Also, do not discount the affordable cost, which is about 10 rubles. for a daytime appointment. The disadvantages of the drug include its prohibition on admission in patients with severe renal and hepatic insufficiency, as well as with lactose intolerance.

Amlodipine (Norvasc)

Rating: 4.7

Amlodipine is a slow calcium channel blocker and an extremely popular drug for the treatment of hypertension. It is worth noting that besides the first and original manufacturer of amlodipine, Pfizer, there are more than 3 dozen different copies of 'other amlodipines' in different dosages. Standard Norvasc is produced in tablets of 5 and 10 mg.

In addition to lowering blood pressure, amlodipine has an antianginal effect, that is, it prevents the occurrence of an attack of angina pectoris. Amlodipine is able to lower blood pressure for a long time, dilating blood vessels. When you take one Norvasca tablet, your blood pressure is reduced for a whole day. Due to such a stable effect, it is necessary to take Amlodipine once a day, with a small amount of water.

The initial dose is usually 5 mg, but, at the discretion of the attending physician, it can be doubled. The original amlodipine, or Norvasc, can be purchased in a minimum dosage of 5 mg, calculated for a month of admission, at a price of 460 rubles. The most affordable analogue of domestic amlodipine can be purchased in the same dosage and in the same quantity from the Ozone company for only 10 rubles. per packing. But the question remains about the quality of the initial substance used by the original Pfizer company and the quality of the domestic drug. The choice is made by the patient.

Advantages and disadvantages

The advantages of amlodipine include a persistent and long-term hypotensive effect, as well as the ability to immediately treat both hypertension and angina pectoris. For this universal action, he earned his place in the ranking. The negative sides include an overdose, in which blood pressure can seriously decrease and heartbeat develop, the occurrence of other adverse reactions from various organ systems, and it is also required to use amlodipine very carefully in patients with hepatic insufficiency and aortic stenosis.

Prestarium (perindopril)

Rating: 4.6

This drug also belongs to ACE inhibitors, but is a more modern medicine. The standard tablet dosage is 2.5 mg, 5 mg and 10 mg. Prestarium is effective in the treatment of hypertension of any severity, which is an obvious plus. It lowers both systolic and diastolic blood pressure. This drug is also able to maintain a hypotensive effect for a day after a single dose. This medicine can restore the elasticity of large vessels and reduce the overdevelopment of the left ventricle of the heart. The drug is also indicated in the treatment of coronary heart disease, and in patients with vascular diseases of the brain for the prevention of stroke.

It is necessary to use the drug once a day, preferably in the morning, one tablet at a time. The duration of the course and the transfer to higher dosages is carried out by the attending physician. The original Prestarium in an average dosage of 5 mg, calculated for a month of admission, can be purchased from 350 rubles. per packing. The drug has many different analogues: Perineva, Perindopril, Hypernik, Kovereks.

Advantages and disadvantages

The advantage of Prestarium is the ability to be prescribed as monotherapy, that is, to be the only drug for high blood pressure. It can also be prescribed in conjunction with other means. The negative aspects include side effects, which most often manifested themselves as headache, dizziness, tinnitus, but at the same time directly depended on the dose. Also, the negative aspects include the rise in blood pressure at the beginning of treatment. Therefore, a cardiologist should monitor the patient's condition, and the combination of Prestarium with other drugs at the initial stage of treatment.

Veroshpiron (spironolactone)

Rating: 4.5

Finally, we must not forget about popular drugs among the people, which include potassium-sparing diuretics. Usually, strong diuretics, such as furosemide or Lasix, are able to remove potassium from the body, which is manifested by unpleasant sensations, disruption of the heart, pulling cramps in the calf muscles, especially at night.

Veroshpiron is a drug that removes urine, but at the same time conserves potassium in the body, and its effect is more 'mild'. This original spironolactone is produced by the Hungarian company Gedeon Richter, 20 tablets – 25 mg costs about 70 rubles. You also need to take this drug under the supervision of a doctor, but no more than 4 tablets per day.

Advantages and disadvantages

The advantages of Veroshpiron include a wide range of indications, ranging from arterial hypertension and heart failure to edema and endocrine disorders. Also, this drug acts mildly, and the effect is observed on the 3-5th day of treatment. Among the disadvantages – Veroshpiron should be used carefully for many endocrine diseases, and in the treatment of hypertension, it cannot be prescribed as the only medicine, and must be used together with other drugs.

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Attention! This rating is subjective and does not constitute an advertisement and does not serve as a purchase guide. Before buying, you need to consult with a specialist.