8 modern remedies for anxiety

Review of the best according to the editors. About the selection criteria. The the material is subjective, is not advertising and is not serves as a guide to the purchase. Before purchase is needed consultation with a specialist.

There are many on the Internet drug review sites. And, including find information on many medications that are recommended from anxiety. But, unfortunately, these articles are written by non-specialists, and therefore, they often get drugs that do not have anxiety no relation. For the most part, these reviews are dedicated to over-the-counter means of free leave, and therefore means anxiety treatments are Novopassit, Afobazol, Persen-Forte, tincture of valerian and other medications.

These are wonderful sedatives, but the trouble is: in global (and domestic) clinical guidelines on the treatment of anxiety disorders, they do not appear. In fact, world practice for the treatment of anxiety disorders implies the use of completely different drugs, and they are prescribed by a specialist. Before proceeding to the story about these drugs, it is necessary decide what anxiety is.

But what is anxiety?

The fact is that medicine is a science. And all the concepts and diagnoses, including anxiety, should be clearly defined. And in the reviews medicines written by lay people, medicines for anxiety replaced by sedatives, anxiety disorder called stress. Also in this group you can read about medicines for fear, excitement and so on.

Actually, a special emotion is called anxiety. paint, which is always vague, and associated with trouble, who are waiting for a man in the future. An alarm can be described as vague, gnawing unpleasant foreboding. All events that were in the past and which we experienced – to anxiety have no relations. It can be painful for the past, it can be embarrassing, insulting, bitterly. You may be aware that we have made a mistake, but never We will feel past anxiety. We won’t, with only one exception: if actions done by us in the past can greatly hurt us in the future. Here, in this case, is also an alarm.

Anxiety and fear are different conditions. Fear completely specific. You can be afraid of death, spiders, motorcycles, dental doctors, the darkness. Anxiety is always abstract, blurred, and therefore experienced by man is much worse than fear. At least you can avoid the situation when you are scared. Get rid of anxiety yourself is very difficult.

This drug review focuses on a specific form anxiety called generalized anxiety disorder (GTR). Not every alarm fits these criteria. So here they:

  1. anxiety state that is difficult to control and she lasts at least 6 months;
  2. the nature of anxiety is not caused by anything definite, and impossible name exactly the circumstances with which anxiety is associated and what you need do to avoid her;
  3. this unpleasant condition is accompanied by many symptoms: impaired concentration, irritability appears, insomnia occurs, the person is restless, is on the verge of collapse. Perhaps a trembling appears, you can not relax;
  4. vegetative reactions occur, such as dry mouth, sweating, decreased memory;
  5. sometimes wariness and irritability appear;
  6. at the same time, a person often experiences strange experiences and feelings of guilt;
  7. it’s hard to suppress this unpleasant anxiety.

In simple terms, the criteria of the so-called generalized anxiety disorder. If several the listed symptoms are there, then there is nothing shameful to contact an intelligent doctor – psychiatrist, talk about these problems, the psychiatrist will diagnose and prescribe if necessary treatment.

Therefore, in the event that you are with these complaints, which meet the GTR criteria, contact another specialist and he will not advise you to consult a psychiatrist, but prescribe tincture motherwort, you are looking for a true professional. Appeal to to a psychiatrist does not at all mean admitting himself crazy. For of this there are other diagnoses, for example, bipolar a disorder, a former manic-depressive psychosis, or schizophrenia. What is the treatment for serious anxiety disorder professionals?

Comments before drug review

There will be many strangers in this drug review names. This should not be feared, since all drugs comply with official clinical guidelines Accordingly, after reading this review, a person will know how to treat anxiety disorder seriously and professionally and article written solely for educational purposes.

Since these drugs are sold only by prescription, this A review cannot be called a rating. Rating is a list popularity. There is no “popular” or “unpopular drugs.” There is the concept of “testimony” and “contraindications.”

In the list of drugs, an international generic is given first. name, INN. In brackets are various commercial varieties. of this medicine, and usually in the first place comes the original the drug that was developed very first. Usually, the original product is always more expensive than its commercial copies. But with this is always the largest drug evidence base and it is the least tool the number of side effects, and the purest drug substance. The manufacturer of the original drug is always strictly monitors his business reputation.

It should be warned that the treatment of generalized anxiety disorders by original, best means expensive lesson. The drugs are pretty expensive by Russian standards expensive, but it’s a fee for quality, for a minimum amount side effects, and most importantly – for the result. Choose which Of course, the patient always decides to buy the drug. But insist and advising you to choose quality or low cost is the doctor’s task. So, what medicines do professionals use for treating serious anxiety disorders, and what are their advantages and minuses?

Anxiety Review

Nomination a place Name of product price
SSRI Review – Selective Reuptake Inhibitors serotonin 1 Paroxetine (Paxil, Rexetin, Adepress) 322 rub
2 Escitalopram (Cipralex, Selectrum, Lenuxin, Elicea) 437 rub
3 Sertralin (Zoloft, Aleval, Asentra, Serenate, Serlift, Stimuloton) 1 149 rub.
Overview of SSRIs and Tricyclic Antidepressants 1 Clopiramine (Anafranil) 317 r
2 Duloxetine (Simbalta) 3 234 rub.
3 Venlafaxine (Velaxin, Velafax, Venlaxor, Newvelong, Efevelon) 1 174 rub.
Benzodiazepines 1 Diazepam (Relanium, Seduxen, Sibazon, Valium)
Is there an over-the-counter remedy for anxiety? – There is! 1 St. John’s Wort – (Gelarium, Neuroplant, Negrustin, Deprim) 1 436 rub.

SSRIs – Selective Reuptake Inhibitors serotonin

Medicines with such a complex name are a group of real antidepressants, modern third generation drugs. They specifically designed to treat depression and serious forms anxiety. Significant experience in the treatment of these diseases with SSRIs and they replaced the old drugs from the tricyclic antidepressant group.

Their predecessors had side effects associated with with drug sedation. There was a drop in arterial pressure with a sharp rise, or orthostatic hypotension, and cholinolytic side effects were also expressed. To them difficulty urinating, dry mouth, constipation, tachycardia, erectile disorders. These side effects are remembered everyone who used to take old antihistamines, such as diphenhydramine, suprastin or pipipolfen.

Antidepressants from the SSRI group, such roughly expressed no side effects. The mechanism of action of these drugs lies in the fact that they retain serotonin, which is called “hormone of good mood” between neurons in the synaptic cracks, and do not allow it to collapse. Therefore, the “hormone of good mood “lasts longer than under physiological conditions. This allowed the use of these funds, including for treatment anxiety disorders.

Paroxetine (Paxil, Rexetin, Adepress)

Popularity Rating: 4.9

PAROKSETIN (PAKSIL, REKSETIN, ADEPRESS)

Rexetin is a typical representative of reverse inhibitors. capture serotonin, and has a psychostimulating effect. Besides for the treatment of generalized anxiety disorder, it is used also during panic attacks, and especially when a person is afraid to be in an open and crowded place, or in a crowd. This phenomenon called agoraphobia. Helps Rexetin Also Deal With syndrome of obsessive thoughts and actions, that is, OCD �(obsessive-compulsive disorder), as well as with depression of various origins when accompanied by anxiety. The use of Rexetin helps prevent relapse of anxious disorders.

With the anxiety disorder that wears so long and generalized nature, the recommended dose of the drug begins with one tablet, i.e. 20 mg. In some cases, it can be double, but naturally, by decision of a psychiatrist. The maximum daily dose that a person can take with this type of anxiety is 2 and a half tablets, or 50 mg per day. Rexetin is produced by the Hungarian company Gideon Richter, and the cost of a package of 30 tablets of 20 mg is 765 rubles.

Advantages and disadvantages

The advantage of Rexetin and Paxil is the fact that, compared with tricyclic antidepressants they are much smaller and less common cause their side effects, such as drowsiness and dryness during mouth, but you can not suddenly cancel the drug. It may cause various unpleasant symptoms, such as a feeling of fear, tingling in fingers, tremor, sweating. Therefore after a long course of use, the doctor must warn that begins a period of slow dosage reduction. Every second day the dose is reduced. In some cases, there may be side effects, but, as a rule, they pass over time, and arise only on sufficiently high doses. Most often, the patient experiences nausea, but not more than in 12% of cases. Sometimes there is sweating, in 9% of cases, and dry mouth is noted by 7% of all subjects.

Escitalopram (Cipralex, Selectrum, Lenuxin, Elicea)

Popularity Rating: 4.8

ESCITALOPRAM (CIPRALEX, SELECTRA, LENUKSIN, ELITSEY)

Cipralex is also an antidepressant from the SSRI group, and is indicated with the same disorders. Cipralex treats depressive episodes of any severity, and prescribe this drug with anxiety disorder should usually be once a day, 10 mg. IN in some cases, depending on the patient’s perception of the drug You can double the dosage, but this will be the maximum dose.

Cipralex should be treated for a long time, the smallest the duration of treatment is 3 months. But in order not to relapses of chronic anxiety occurred, you can use the tool in for six months, by decision of a psychiatrist. Produces this the drug is Lundbeck company from Denmark, and its price is quite high: for a pack of 14 tablets, which is enough for two weeks of treatment, should, on average, pay 2200 rubles. If such a price is not at pocket, then you can choose a domestic analogue, escitalopram production company Canonfarm production. Then a pack of 28 pills, designed for a whole month of admission, will cost 551 rubles. But the question of comparative effectiveness remains open.

Advantages and disadvantages

Of the benefits of this drug, it is noted that if side effects and arise, then only at the very beginning of treatment, at the first or second week, and then their profile is smoothed, and they can even completely disappear. The most common change in appetite is can be both reduced and increased. The patient may have unusual dreams, sometimes a slight tingling sensation in the fingers type of paresthesia, yawning attacks may occur. Often slight nausea, as well as changes in stool, sweating increases. It is separately noted that if the patient used hypericum preparations, then this can increase the frequency and severity of side effects. However, escitalopram and cipralex is a highly effective drug and is used worldwide for the treatment of severe anxiety disorders.

Sertralin (Zoloft, Aleval, Asentra, Serenate, Serlift, Stimuloton)

Popularity Rating: 4.7

SERTRALIN (ZOLOFT, ALEVAL, ASENTRA, SERENATE, SERLIFT, STIMULOTON)

The last representative of this group in the review is the drug. Zoloft. It is also used to relieve various depressive episodes, for the prevention of depression, for the treatment of neurosis obsessive states, or obsessive-compulsive disorders. it the tool copes with a panic attack, with various forms of social phobia.

It is necessary to use the drug once a day, regardless from eating, and, which is especially convenient, you do not need to take it in any particular time. So, Paxil and Rexetin need take only in the morning, and Zoloft can already be taken when at will, the main thing is not to miss the deadline. Recommended dosage for generalized anxiety disorder begins with doses of 50 mg per day, and if necessary, by the decision of a doctor, it can be increase to 150 mg, but this will already be the maximum dose.

In this case, the dose increase should be gradual: the interval should make at least a week before the next increase. Zoloft is produced by Pfizer, and a pack of 28 tablets, calculated for a month of administration in an average dosage of 100 mg, costs 1250 rub.

Advantages and disadvantages

Zoloft is quite safe, it can also be used in child psychiatry, starting at the age of six. For treatment seniors do not need to specifically adjust the dose, but if there is chronic liver disease, then the remedy is necessary take in a lower dose, or observe a patient with a special caution. A big plus of sertraline in general, and Zoloft’s in particular, is the fact that he has virtually no symptoms of an overdose even when it is prescribed in large doses.

But it is strictly forbidden to use during the treatment of anxiety Sertraline alcohol disorders, as this can lead to the development of severe poisoning, up to a coma. If a the patient takes sertraline, then he should not take others drugs that affect the exchange of serotonin. Case may end with malignant antipsychotic syndrome. To such drugs include triptans, which are used to treat migraines, as well as monoamine oxidase inhibitors.

Malignant antipsychotic syndrome is very serious a disorder that can be fatal, here why treatment with serious prescription drugs that have high efficiency, must necessarily pass through doctor’s prescription and under the supervision of a physician.

Overview of SSRIs and Tricyclic Antidepressants

They have long been used in the treatment of serious anxiety disorders. tricyclic antidepressants. Although they have lost their place SSRIs, but still apply. They have developed a very solid evidence base, therapeutic strength dx is quite high. Previously, it was the main group of antidepressants, but gradually they were supplanted by more modern means, but some of them have not lost their significance, especially in the treatment of prolonged and severe anxiety.

Tricycles are relatively inexpensive, they can be purchased at any pharmacy, prescription, and recall that according By law, the prescription remains in the pharmacy, and is not returned to the hands issued. Also, tricyclic antidepressants (TCAs) are convenient for those what is well known, at what concentrations they treat, and at what concentrations may show toxic effects. In addition, during many laboratories measure concentration tricyclic antidepressants in the blood and even their metabolites. Of of such drugs in the treatment of severe anxiety, clopiramine is used, better known as Anafranil.

Another group of drugs is the so-called selective serotonin reuptake inhibitors not only about which said, but also noradrenaline (SSRI). Otherwise they are also called double-acting antidepressants. Plus of this group is enough low severity of side effects, good tolerance and great power of action. They even outperform drugs from the first group (SSRIs), but do not reach a little tricyclic antidepressants. They are used as drugs with a larger security level. To such means, according to modern recommendations include venlafaxine and duloxetine. About these three tools will be described below.

Clopiramine (Anafranil)

Popularity Rating: 4.9

KLOPIRAMIN

Tricyclic antidepressant Anafranil indicated for treatment anxiety and depression, including in old age. His used to treat chronic pain, and in children older than 5 years – for the treatment of nocturnal enuresis.

In case of anxiety, anafranil is first prescribed in a minimum dosage – 75 mg, and the maximum daily dose of 200 mg. Moreover, the dose increase goes after a few days, and no more than 25 mg. Daily dose cannot be increased. When the condition improves, they switch to maintenance dose, going down in a dose lower. Average the duration of treatment is about 6 months. Launches Anafranil Novartis Pharma company, and a package of 30 tablets of 25 mg each is worth an average of 326 rubles. Therefore, with an average dosage of 100 mg per day such packaging is enough for a week with a little.

Advantages and disadvantages

Anafranil has all the standard tricyclic side effects. antidepressants. There are a lot of them, and not everyone is well tolerated this is a cure. Overdose may cause symptoms intoxication, and in the elderly there are a large number contraindications to the appointment of TCA. Strongly forbidden during pregnancy, since it can cause congenital malformations fetus. And finally, there is the phenomenon of cross-resistance. If the patient turned out to be ineffective any tricyclic the antidepressant that he had taken before, then Anafranil him too will not help. But in the event that it helps – it really relieves anxiety, since the strength of the therapeutic effect in TCAs one of the highest.

Duloxetine (Simbalta)

Popularity Rating: 4.8

DULOKSETIN

This medicine is not only used for depression. and anxiety, as well as in patients with diabetes, if they legs are very sore due to diabetic polyneuropathy. Take Simbalt first you need one tablet once a day, and according to the doctor’s decision, the dose can be doubled, 120 mg is maximum dose. Simbalta capsules must be swallowed whole, not in Do not chew or crush. The fact is that the drug is absorbed only after entering the intestines, and gastric juice destroys this expensive drug. Launches Simbalta Swiss company Eli Lilly, and one blister of 14 tablets of 60 mg costs 1850 rubles. Thus, two weeks of treatment with the original Duloxetine will cost almost 2,000 rubles. But calm expensive…

Advantages and disadvantages

Simbalta is tolerated, of course, better than Anafranil, and from side effects are most often observed slight dizziness, sometimes dry mouth, possibly drowsiness, or vice versa insomnia. In no case should you take this drug together with monoamine oxidase inhibitors (MAO), and this must be track the attending physician.

Venlafaxine (Velaxin, Velafax, Venlaxor, Newvelong, Efevelon)

Popularity Rating: 4.7

Venlafaxine (Velaxin, Velafax, Venlaxor, Newvelong, Efevelon)

Velaxin is another drug from this group. It is shown in pure form for the treatment of anxiety disorders and depression, and for the prevention of their relapses. It is recommended to take the drug by one capsule 1 time per day with meals. In some cases, you can increase daily intake to 2, and even to 3 (maximum) capsules, but only by a doctor’s decision in connection with severe anxiety disorder, and the dose increase should go no more than 2 weeks later. After how clinical improvement and regression will be achieved anxiety, the dose again slowly decreases to a supportive one.

In case of depression, continued treatment for at least 6 months, in in case of anxiety disorders – at least 3 months. Releases drug Velaxin Hungarian company Egis, and a package of 28 capsules prolonged action costs 1110 rubles.

Advantages and disadvantages

Patients who take this medication should tell to the doctor about all thoughts associated with suicide (with depression), and his reception may cause in some cases the need to move, anxiety and inability to sit still. So peculiar a form of psychomotor agitation can be during the first several weeks after starting therapy. There are also side effects. Patients often have unusual dreams, sometimes – palpitations, sweating, in some cases joint pain appears. Therefore, treatment should be carried out under careful medical supervision.

Review of benzodiazepines

Benzodiazepines are a long-known and widely used group. drugs that affect gamma-aminobutyric receptors acids (GABA). Many of them know how the so-called tranquilizers or sleeping pills. But including they are used to treat anxiety, panic attacks, some types of epilepsy, and including for the treatment of anxiety.

Among them are drugs diazepam, lorazepam and weaker phenazepam. Phenazepam has already been described in a drug review for insomnia (read here), therefore repeat the data on phenazepam will not be here. It should only be indicated that the recommended dose phenazepam for the treatment of generalized anxiety disorder is from 1 to 3 mg daily, but at the same time, unlike all previous drugs described in this article, he has the lowest level of evidence. This does not mean that phenazepam does not cure. alarming. He treats, but still worse than the above drugs. Since both diazepam and lorazepam are agents of the same group, we will describe as a typical representative of diazepam.

Diazepam (Relanium, Seduxen, Sibazon, Valium)

Popularity Rating: 4.9

DIAZEPAM (RELANIUM, SEDUXEN, SIBAZON, VALIUM)

Diazepam, or Relanium, is widely used, ranging from treatment muscle cramps with tetanus, before psychomotor agitation various etiologies. It is also used to treat neurosis with manifestation of anxiety. In this case, the drug is prescribed in a dosage from 5 to 15 mg, with a gradual increase in dose. In case if anxiety is combined with depression, and the patient talks about his suicidal thoughts, then he must fully trust the doctor, and be with him in constant contact. In case of an acute anxiety attack, you can repeat the pill after three to four hours, but by decision a doctor. Produces diazepam (Sibazon) domestic enterprise Organics, and a pack of 20 tablets of Sibazon 5 mg each only 22 rubles. This, of course, is immeasurably cheaper than expensive imported antidepressants. By the way, diazepam is not an antidepressant. is an.

Advantages and disadvantages

The advantage is the cheapness and speed of action. Generally at present diazepam time in its various forms is not the main way relief of anxiety disorder and for long-term therapy tries not to apply, despite the high level evidence and the great power of recommendations. He really relieves anxiety, but most likely in emergency situations. For planned therapy, it is not suitable, because after taking the pills Diazepam must not drive or work with dangerous machines and mechanisms.

Antipsychotics

Antipsychotics, or antipsychotic drugs – this is a classic “big psychiatry.” With their help, psychoses stop, these drugs treat schizophrenia, hallucinations, delusional disorder, excitement, manic state. However, the indications are atypical apsychotics can be used to treat generalized anxiety disorder. It will not list the virtues and the disadvantages of each drug, since antipsychotics are especially serious means, and for a person without a medical education this information will not give anything. Enough to list those antipsychotics, which are used to treat serious anxiety disorders. This is the Seroquel company Astrazeneca, Truxal, or chlorprotixen Lundbeck production. This is Azaleptin (Leponex).

It should be understood that antipsychotics are always “heavy” artillery, and is not just used in patients with generalized anxiety disorder, but only with the disorder that resistant to antidepressant therapy and other treatments (psychotherapy). Sometimes experts combine in therapy antidepressants and antipsychotics. But here everything is far from being so just.

Recent studies have shown that these antipsychotics may upset the balance of feelings of satiety, appetite and hunger, which will lead to weight gain. This side effect often enough expressed in their application. Some studies show that atypical antipsychotics can cause changes in carbohydrate metabolism and insulin resistance. In addition to such metabolic complications, not the risk of heart rhythm disturbance is also excluded, since all atypical antipsychotics can potentially lengthen electrocardiographic interval QT

Therefore, with anxiety, drugs from the group of antipsychotics used very rarely. What to do? All drugs listed in the article are extremely serious, prescription, and only those working with such patients can write them out psychiatrist. Neither the therapist, nor even the neurologist has written them rights. Is there really no way out? Is it really necessary to go only to to the psychiatrist? For serious and prolonged anxiety disorder – naturally yes.

Is there an over-the-counter remedy for anxiety? – There is!

Above was enough talked about serious drugs that doctors prescribe to treat serious anxiety disorders. But what to do if the alarm does not reach those symptoms that were described first? If she is not very prevents to live, but only sometimes “rolls”? In that case there is a great way out, namely: an herbal preparation – St. John’s wort

St. John’s Wort – (Gelarium, Neuroplant, Negrustin, Deprim)

Popularity Rating: 4.9

ANIMALS - (GELARIUM, NEUROPLANT, NEGRUSTIN, DEPRIM)

There are many herbal preparations of St. John’s wort, and in our the country can purchase Gelarium, Neuroplant, Negrustin, Deprim, and even Doppelherz is nervous. In fact, plant materials St. John’s wort is known for its antidepressant and anti-anxiety effect with ancient times, and even in ancient Greece and Rome was used St. John’s wort for the treatment of depression and anxiety. It was different decoctions, tinctures and extracts. Currently, these funds still used for these purposes.

Since 1998, in Western Europe, these drugs received an official license, and a large evidence base. At mild to moderate depression and anxiety their effect was comparable to the effect of the above antidepressants from the SSRI group. Of course, hypericum preparations are safer than prescription drugs. benzodiazepines, antidepressants, and especially antipsychotics. They well tolerated, and cancel hypericum have much less. How to take these “plant anti-anxiety”?

So, Gelarium is used in a dosage of 1 tablet three times a day during meals, and the course of admission should be at least a month. Just after a month there should be an improvement (rapid change mood should not be expected), and the same term applies to all Hypericum preparations.

Advantages and disadvantages

However, there are also disadvantages. One of them will be photosensitization. If the drug is taken in the summer, then you can not be in the open sun, because you can get serious burns. By the way, that’s why this grass was named St. John’s wort. In case of an overdose, fatigue and dryness may occur. mouth, redness, and gastrointestinal upsets. Not less, this is really a way out with a slight alarm upset.

Of course, there is no such medicine that would not have side effects. effects. There is no good without a bad. Therefore if the patient is depressed episode or with anxiety disorder wants to be treated completely without side effects, then he is shown courses of psychotherapy, which are also are part of the clinical guidelines for treating anxiety.

Popularity rating based on analysis of service demand data wordstat.yandex.ru.


Attention! This rating is subjective, not advertising and does not serve as a guide to the purchase. Before the purchase consultation with a specialist is necessary.

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