Review of the best according to the editorial board. On the selection criteria. This material is subjective and does not constitute advertising and does not serve as a purchase guide. Before buying, you need to consult with a specialist.
Despite the fact that nausea and vomiting are very distressing and unpleasant symptoms, the ranking of drugs with antiemetic effects will be surprisingly poor. If we consider remedies for headaches, for arterial hypertension or for the treatment of pneumonia, then you can not only pick up two or three dozen drugs, but combine them into different groups. It is difficult to combine antiemetics into groups, and there are probably not even a dozen original remedies.
Although the cause of nausea and vomiting can be manifold, this symptom requires the use of few drugs. Vomiting can occur with dizziness, neurosis or stress, with motion sickness, when flying on airplanes, and as a side effect of drugs, for example, in cancer patients during a course of chemotherapy.
The reason is that nausea and vomiting, or just vomiting without nausea, when antiemetics are prescribed, is almost never seen as a symptom of intoxication and inflammation. But it is on this occasion that these symptoms most often occur!
If vomiting accompanies acute poisoning, intestinal infection, then this symptom disappears when the underlying disease is treated, antiemetics are not needed. With meningitis, due to irritation of the meninges and the vomiting center of the brain, there is the so-called cerebral vomiting, without nausea. At the same time, an unsuspecting patient suddenly spews out a powerful fountain of vomit without any warning to the body, without the slightest feeling of nausea. With meningitis, antiemetics are also not prescribed, since after the inflammation on the meninges is stopped, vomiting disappears by itself. Therefore, antiemetics fight against the gag reflex, and the point of their application is almost always different links of the arc of this reflex.
Attention! Antiemetics are strictly prohibited for use in acute poisoning, intestinal infections, alcohol intoxication and similar conditions, when vomiting cleanses the body and removes alcohol and microbial toxins from the stomach. The only exceptions would be acute radiation injury and radiation sickness.
This rating includes the most effective and popular drugs for suppressing the gag reflex and reducing the unpleasant feeling of nausea.
- Rating of the best remedies for vomiting
- Motilium, Motilak, Domstal, Motiject, Passages (domperidone)
- Advantages and disadvantages
- Cerucal, Perinorm (Metoclopramide)
- Advantages and disadvantages
- Zofran, Latran, Emetron (ondansentron)
- Advantages and disadvantages
- Dramina, Aviamarin, Ciel (dimensionhydrinat)
- Advantages and disadvantages
Rating of the best remedies for vomiting
| Nomination | a place | Name of product | price |
| Rating of the best remedies for vomiting | 1 | Motilium, Motilak, Domstal, Motiject, Passages (domperidone) | 559 r |
| 2 | Cerucal, Perinorm (Metoclopramide) | 116 RUB | |
| 3 | Zofran, Latran, Emetron (ondansentron) | RUB 675 | |
| 4 | Dramina, Aviamarin, Ciel (dimensionhydrinat) | 182 r |
Motilium, Motilak, Domstal, Motiject, Passages (domperidone)
Rating: 4.9
The active ingredient is domperidone, it blocks dopamine receptors that exist in different parts of the central nervous system. Motilium is indicated for the treatment of chronic diseases of the esophagus, intestines and stomach, accompanied by belching, heartburn, a variety of symptoms of gastric dyspepsia – nausea, vomiting and a feeling of fullness in the gastric region.
It is necessary to take Motilium one tablet half an hour before meals and, if necessary, before bedtime. Each tablet contains 10 mg of domperidone, the maximum daily dose is 8 tablets for adults. Motilium is produced by the pharmaceutical company Janssen Silag, and the cost of one package of 30 tablets averages 670 rubles. The cheapest analogue of Motilium is considered to be domestic domperidone, which is produced by the Ozone company. The average cost for such a package is about 80 rubles.
Advantages and disadvantages
The advantage of Motilium is its rather high efficiency, with a slight urge to vomit, and with mild nausea, sometimes 1 or 2 tablets a day are enough. On the other hand, there are also contraindications. These include gastrointestinal bleeding, severe liver dysfunction, a prolactin-secreting pituitary tumor, and phenylketonuria. But in the event that all indications and contraindications are taken into account, then this remedy will be indispensable in the symptomatic treatment of nausea and vomiting.
Cerucal, Perinorm (Metoclopramide)
Rating: 4.8
The active substance of cerucal is metoclopramide. It acts on the same dopamine receptors as domperidone and is also their central blocker. Cerucal is indicated for use in such diseases as acute gastritis with a feeling of nausea, pylorospasm, when food is retained in the stomach, and its atony. Cerucal is used injectable for intestinal obstruction after surgery, for heartburn, gastroesophageal reflux, for nausea and vomiting in patients in the acute period of stroke, as well as for successful diagnostic techniques, for example, before esophagogastroduodenoscopy.
You need to take Cerucal one tablet half an hour before meals, the average dose for adults is one tablet three or four times a day, but no more than 6 tablets a day. Cerucal is produced by the Croatian pharmaceutical company Pliva, and the cost of 1 package of 50 tablets of 10 mg each averages 120 rubles.
Advantages and disadvantages
The big plus of Cerucal is the ability to carry out long-term therapy, which can be two, three or more months, but not more than six months. Also, Cerucal can be used as a means of additional therapy in the treatment of cytostatics, for example, Azathioprine, Cyclophosphamide and other means to level their side effects. The advantage of Cerucal will be the presence of an injectable form, which quickly helps either to eliminate nausea, or to prevent it, for example, when conducting invasive studies.
Zofran, Latran, Emetron (ondansentron)
Rating: 4.8
It is a modern antiemetic drug produced by the renowned company Novartis, Switzerland. The active ingredient is ondansetron, a xerotonin receptor antagonist. It is known that drugs for the treatment of cancer and cytostatics cause an increase in the concentration of serotonin in the central nervous system, and it is able to stimulate the vomiting center through the parasympathetic system. Ondansentron, by blocking receptors, inhibits the vomiting reflex arc.
Zofran is shown mainly as a concomitant therapy in patients taking cytostatics and chemotherapy drugs, as well as those undergoing radiation therapy. Other indications will be various postoperative conditions when the patient is worried about nausea and vomiting, and often this occurs not only after operations on the gastrointestinal tract, but also with a gradual decrease in the effect of general anesthesia. This product is available in a wide variety of forms: parenteral, lozenge, and strawberry-flavored syrup. Each tablet contains 4 mg or 8 mg of the active agent, and a maximum of 4 8 mg tablets can be taken per day. The first pill is taken one hour before the chemotherapy session.
Absorbable tablets are quite expensive. A package of just 10 8 mg Zofran tablets costs, on average, 2,100 rubles. But there are also more affordable analogues. So, ondansetron, produced by the Israeli company Teva, costs only 306 rubles for the same package.
Advantages and disadvantages
Since this drug is serious, it should not be used in pregnant women, during lactation, and also in children under the age of two. Side effects include a wide variety of allergic reactions, dry mouth, chest pain, headache and fever. Nevertheless, the effectiveness of this drug is so high that even with high-dose chemotherapy, in which a side effect such as nausea occurs in almost 100% of cases, ondansetron can significantly improve the patient's quality of life during this difficult type of treatment.
Note: There is an even more specific antiemetic from this group, this is granisetron, the original drug is Kitril. It produces an even stronger antiemetic effect, and only affects those serotonin receptors that are responsible for the gag reflex. This drug has much higher efficacy and safety, but its cost is even higher. One pack of domestic granisetron, which is obviously cheaper than all foreign drugs, and even more so the original one, is 5,000 rubles per pack of only 10 tablets. The cost of the original Kitril drug can only be guessed at.
Dramina, Aviamarin, Ciel (dimensionhydrinat)
Rating: 4.7
At the end of this small rating of antiemetics, it is necessary to say a few comforting words to those completely healthy people who may experience unpleasant symptoms of seasickness and air sickness, which are car sickness. Antiemetics are also needed for patients with various forms of dizziness, vestibular neuronitis and Meniere's disease, which are often treated by ENT doctors.
For such patients, there is the drug Dramina and its analogs, in which the active ingredient is 50 mg of dimensionhydrinate in each tablet. This agent belongs to the group of blockers of histamine receptors and cholinergic receptors in the central nervous system. Dramina acts on the structures of the vestibular apparatus, on its semicircular canals and special stones, or otoliths. In addition to reducing nausea and vomiting, this remedy significantly reduces appetite, has a sedative effect, slightly reduces allergy symptoms, and helps to reduce dizziness.
It is necessary to use the drug Dramina before meals. With motion sickness, adults are shown taking no more than 6 tablets per day, divided into 3 doses, and with systemic dizziness, Meniere's disease and labyrinthitis, the dosage and frequency of administration is determined by the ENT doctor. The Croatian company Jadran produces Dramina, and a pack of 10 tablets costs 180 rubles.
Advantages and disadvantages
Unfortunately, this drug, despite the pronounced antiemetic effect, is characterized by all the disadvantages of the group of histamine receptor blockers. Often there is anxiety, drowsiness, stuffy nose, constipation and dry mouth, urinary retention, and other unpleasant effects. In case of an overdose, all these symptoms increase significantly, so do not exceed the required dosage.
To top it off, taking the drug Dramina slows down the driver's reaction speed, so you should not drive after taking this drug, and also work with various machines and mechanisms. This drug and its analogs are contraindicated in the first trimester of pregnancy, breastfeeding, epilepsy and glaucoma.
Of course, the list of contraindications and side effects is quite impressive, and some would agree to endure the unpleasant symptoms of motion sickness rather than take a rather crude drug. But with vestibular neuronitis and attacks of dizziness can be so strong that the patient lies, clinging to the bed, it seems to him that the room revolves around him in one direction, like on a carousel, and at the same time he experiences debilitating bouts of repeated vomiting. It is in such cases that Dramina will relieve the patient's condition, while the positive effect will far exceed the above side effects.
Attention! This rating is subjective and does not constitute an advertisement and does not serve as a purchase guide. Before buying, you need to consult with a specialist.
