20 modern antibiotics

Review of the best according to the editorial board. On the selection criteria. This material is subjective and does not constitute advertising and does not serve as a purchase guide. Before buying, you need to consult with a specialist.

Overview of modern antibiotics

Nomination	a place	Name of product	price
An overview of antibiotics for angina, bronchitis and cough	1	Flemoxin Solutab	326 RUB
	2	Amoxiclav	466 r
	3	Sumamed	RUB 400
	4	Levofloxacin	359 r
	5	Suprax	818 RUB
ANTIBIOTIC OVERVIEW for sinusitis	1	Sultasin	RUB 64
	2	Macropen	331 r
	3	Rocefin	501 RUB
	4	Avelox	332 RUB
	5	Isofra	283 r
OVERVIEW OF ANTIBIOTICS for children	1	Cephalexin	89 RUB
	2	Clarithromycin	442 r
	3	Lincomycin hydrochloride	154 RUB
	4	Roxithromycin	147 RUB
	5	Furadonin	177 r
OVERVIEW OF BROAD-SPECTRUM ANTIBIOTICS	1	Wilprafen Solutab	RUB 700
	2	Zinforo	28 302 RUB
	3	Inwanz	RUB 1,650
	4	Cubicin	RUB 5,747
	5	Maxipim	192 RUB

An overview of antibiotics for angina, bronchitis and cough

Inflammatory diseases of the upper respiratory tract are among the most common in clinical practice. Diseases such as tonsillitis and bronchitis affect both children and adults. Sometimes these pathological conditions can be caused by viruses, but often a bacterial infection also joins. In this case, it is necessary to use antibacterial drugs (antibiotics). It should be recalled that antibiotic therapy should be carried out only after a complete examination of the patient, diagnosis and verification of the sensitivity of the flora to one or another antibiotic.

A sharp increase in body temperature, an increase in signs of general intoxication (weakness, headache and muscle pain, dizziness), cough with discharge of purulent sputum may indicate the addition of a bacterial infection. This article will review the overview of the most affordable and effective antibiotics for angina, bronchitis and cough in adults.

Flemoxin Solutab

Popularity rating: 4.9

Antibiotic Flemoxin Solutab (Amoxicillin) from the aminopenicillin group is available in the form of soluble tablets of 20 pieces per pack. There are several basic dosages: 0.125g, 0.25g, 0.5g, 1.0g. Amoxicillin is the main active ingredient that inhibits the growth and development of many gram-positive and gram-negative bacteria (pyogenic cocci, which most often provoke inflammatory diseases of the upper respiratory tract).

However, this antibiotic was included in the review because it is used not only for angina and bronchitis – it can also inhibit the growth of some intestinal bacteria that provoke coli enteritis and inflammatory processes in the urinary organs.

Advantages and disadvantages

The main advantages of this medication are fast and complete absorption in the gastrointestinal tract, pleasant taste, and the possibility of using it from early childhood. Another advantage of Flemoxin Solutab is that it can be drunk both before and after meals (and even during meals). With the correct use of this antibiotic, a pronounced therapeutic effect develops from the first hours. But you can notice it after a few days.

A number of disadvantages include, first of all, frequent allergic reactions that occur after using the drug, high cost (relative to analogues), as well as the inability to suppress the growth of bacteria that produce an enzyme such as beta-lactamase (this enzyme destroys penicillins). In general, Flemoxin has much more advantages, therefore this remedy is often used for inflammatory processes that occur in the upper respiratory tract. Price – 200 rubles.

Amoxiclav

Popularity rating: 4.8

This is an antibiotic from the same group as Flemoxin Solutab – it belongs to the group of aminopenicillins. Amoxiclav (amoxicillin and clavulanic acid) is produced in the form of tablets, 14 pieces per package. There are different dosages of this antibiotic: 0.25g, 0.5g, 0.875g each, but it should be noted that the amount of clavulanic acid remains unchanged and is 0.125g. The price of the antibiotic is 350 rubles.

Advantages and disadvantages

As mentioned above, in addition to the main active ingredient – Amoxicillin, the drug contains clavulanic acid, which plays an important role in the treatment of bronchitis and sore throat caused by bacteria that synthesize beta-lactamase. Since this enzyme is able to destroy penicillins, clavulanic acid blocks it, thereby achieving a more pronounced and faster effect. Another advantage is that the drug has little effect on the functioning of the gastrointestinal tract.

The disadvantages include only the fact that Amoxiclav, like all other penicillins, often causes allergic reactions (therefore, before prescribing them, it is imperative to conduct a sensitivity test). A violation of the intestinal and vaginal microflora (dysbiosis and dysbiosis) is possible, therefore, Amoxiclav is always prescribed together with probiotics.

Sumamed

Popularity rating: 4.8

The antibiotic belongs to the group of macrolides, available in the form of capsules, tablets, suspension and lyophysylate for injection. The approximate price is 400 rubles. Sumamed (Azithromycin) actively inhibits the production of bacterial cell wall proteins, which prevents the rapid growth of bacteria. Sumamed is often used to treat chronic tonsillitis (sore throat) and lingering bronchitis. It is especially recommended to take it to those patients who, due to individual intolerance, cannot be treated with penicillin antibiotics.

Advantages and disadvantages

The advantage of Sumamed is that it is an extremely active drug that does not require frequent use, and it rightfully got into the review. It has a good effect of accumulation in the organs and tissues of the body, a rather long period of decay and half-life, and also affects not only aerobic bacteria (which develop in the presence of oxygen), but also anaerobic (multiplying without oxygen). Sumamed makes it possible to treat inflammatory processes of the upper respiratory tract if they are caused by chlamydia or mycoplasma. The antibiotic is usually well tolerated (even with prolonged courses), rarely causes hypersensitivity reactions. The disadvantage of this drug is its high cost.

Levofloxacin

Popularity rating: 4.7

The drug is available in the form of tablets and injection solution. Levofloxacin is an inexpensive but quite effective drug, the price of which is 100 rubles. The antibiotic belongs to the group of fluoroquinolones, acts primarily on the DNA of bacteria, thereby preventing them from multiplying. It is used if the patient has an allergic reaction to both penicillins and macrolides, which does not happen very often. Levofloxacin acts on a large number of different bacteria, which is why it is highly effective.

Advantages and disadvantages

The main advantage, as already mentioned, is the wide spectrum of action of this antibiotic, therefore it can be used in cases where angina or bronchitis is caused by several types of bacteria (mixed infection). The antibiotic is rapidly absorbed and metabolized, instantly acting on the genetic apparatus of microorganisms. Another unconditional advantage is the low price.

However, a wide spectrum of action is not only an advantage, but also a disadvantage of Levofloxacin. By killing pathogenic microorganisms, the drug also destroys the natural microflora of the body. Therefore, this medicine can be used only in short courses and only under the supervision of a doctor. Otherwise, there is a high probability that dysbiosis or fungal lesions of the skin and mucous membranes will develop. There are frequent cases when allergic reactions develop against the background of taking Levofloxacin, therefore it is not recommended to prescribe the drug in childhood. Nevertheless, the antibiotic was reviewed as a representative of active and modern fluoroquinolones, and side effects are an inevitable consequence of any active drug.

Suprax

Popularity rating: 4.7

The antibiotic belongs to a number of cephalosporins and is available in the form of capsules of 0.2 and 0.4 g. Suprax (Cefixime) inhibits the reproduction of various kinds of bacteria, suppressing their division in the early stages. Use this remedy (like all other cephalosporins) for bronchitis and angina only if the patient has a hypersensitivity reaction to all of the above groups of drugs. Often Suprax is used for the complex therapy of protracted bronchitis or tonsillitis caused by several types of microorganisms.

Advantages and disadvantages

The main advantage is the effectiveness and speed of antibiotic action. It can be used even in childhood (Suprax is prescribed if the patient goes to the hospital late, and the infection progresses and urgent help is needed). The antibiotic is absorbed very quickly and begins to act, and its long half-life allows it to be used 1-2 times a day.

The disadvantages of Suprax are its high allergenicity, as well as the need for maintenance therapy in the form of immunostimulants and probiotics, which is aimed at preventing mycoses (fungal infections) and dysbiosis. The price is quite high and amounts to 630 rubles.

Review of antibiotics for sinusitis

Sinusitis is a disease that is inflammation of the paranasal sinuses, accompanied by bursting pain, fever, and purulent nasal discharge. When such symptoms appear, you should immediately consult a doctor to carry out the necessary research and make a diagnosis. Because in most cases, sinusitis is caused by bacteria, antibiotics are a must. However, they are used only if the patient has a weakened immune system and the body cannot cope with this infection on its own.

The need to use antibacterial drugs for prolonged sinusitis is justified by the fact that an infection from the sinuses can enter the cranial cavity or spread through the hematogenous route (through the blood vessels) to other organs. With an untimely appeal to a medical institution, there is not only a risk of complications, but the likelihood of the disease becoming a chronic form increases, which is fraught with frequent inflammatory processes in the upper respiratory tract. This review is based on the preferences of the professional medical community.

Sultasin

Popularity rating: 4.9

An antibiotic from the group of protected aminopenicillins, which is available in powder form in vials (1.5 g each). It is diluted with saline or local anesthetics and injected into the body (intravenous or intramuscular).

The mechanism of action of protected aminopenicillins is that they bind to receptors on the surface of bacterial cells (there are no such receptors in the body, therefore drugs in this group do not act on healthy cells and tissues). After that, the aminopenicillins inhibit the production of proteins, which are a constituent part of the bacterial cell wall. In addition, Sultasin (Ampicillin and Sulbactam) affects the enzyme penicillinase (beta-lactamase), which is produced by some strains of bacteria and inhibits the activity of the main active ingredient. As a result, even resistant bacteria are killed by the action of Sultasin.

Advantages and disadvantages

The main advantages of this drug are the effectiveness and speed of action, and the antibiotic can also be used to treat sinusitis in childhood. Another advantage is the low price, which is 70 rubles.

The disadvantages of protected aminopenicillins (including Sultasin) are a fast half-life (the drug must be used frequently) and frequent allergic reactions. In addition, Sultasin affects the gastrointestinal tract and often causes dysbiosis.

Macropen

Popularity rating: 4.8

Macropen (Midecamycin) is an antibiotic from the macrolide class that has a bacteriostatic effect (actively inhibits the growth of microorganisms for a long period of time). It is sold as a powder for oral use, but the most common tablets are 0.4g (16 per pack).

Advantages and disadvantages

Since the drug has a bacteriostatic effect, it can be used for sinusitis, prone to prolonged or chronic course. Macropen is one of the most preferred drugs if the patient has an allergic reaction to penicillins (and this happens quite often), and this allowed him to get into the review. Macropen rarely causes any side effects and hypersensitivity reactions; when taken, intestinal dysbiosis occurs much less often. Another advantage is the long half-life, so sometimes 1-2 tablets a day are enough. The drug is suitable for the treatment of mixed infections (caused by several types of microorganisms).

The disadvantages of the drug include a rather high cost, which today is 220 rubles. It is undesirable to use Macropen during pregnancy, lactation and early childhood (in such situations, it is used only in extreme cases).

Rocefin

Popularity rating: 4.7

An antibiotic from the cephalosporin group has long been used to treat various inflammatory diseases, including sinusitis. The drug has a bactericidal effect (destruction of microorganisms), while it is active against a much larger number of pathogens than the above-described penicillins and macrolides. Rocefin (Ceftriaxone) is produced in the form of a powder in vials of 1 g. It is intended for intramuscular and intravenous administration, after dissolving the contents of the vial in saline or local anesthetic.

Advantages and disadvantages

As already mentioned, Rocefin can affect a large number of different microorganisms. Moreover, it has a long half-life, so the patient does not need to worry about taking the medicine every few hours – usually 1-2 injections a day are enough. This fact allowed Rocefin to be included in the compliance review, that is, the ease of use, which leads to high patient adherence to treatment.

Of the shortcomings, the most significant is the fact that often penicillin intolerance is combined with an allergy to cephalosporins, so a test must be performed before use. Another disadvantage is the fact that Rocefin does not inhibit beta-lactamase, which is synthesized by some bacteria as a protective enzyme. The price of the drug is quite high and amounts to 450 rubles. During pregnancy, during breastfeeding and in early childhood, Rocefin should be used with extreme caution. Requires the appointment of supportive therapy, which will reduce the risk of dysbiosis and fungal infections.

Avelox

Popularity rating: 4.6

The antibiotic Avelox (Moxifloxacin) belongs to the 4th generation (most modern) fluoroquinolones, and this allows him to lead the review in this group. This group of antibiotics is 100% synthetic – such substances do not occur in the environment, but are created artificially. Avelox is available in the form of tablets of 0.4 g and solution for injection.

Advantages and disadvantages

The main advantage and reason why Avelox is often used for sinusitis of unexplained etiology (origin) or for mixed infection (including those caused by mycoplasmas and chlamydia) is explained by the fact that this drug has a wide spectrum of action and can produce in just a few days the necessary therapeutic effect.

Avelox also has enough disadvantages. The medicine is foreign to the body (as already mentioned, it is completely synthetic), therefore, allergic reactions and dyspeptic phenomena (nausea, vomiting, diarrhea) can often be observed. In addition to gastrointestinal motility, Avelox also affects the intestinal flora – it inhibits it and leads to the development of dysbiosis, to which secondary infections (for example, fungal infections) often join. The drug should not be used during pregnancy, sometimes it is used to treat sinusitis in children, however, this requires serious indications. The price of an antibiotic is 600 rubles, which makes it a rather expensive drug.

Isofra

Popularity rating: 4.5

This is a local antibiotic, which is available in the form of a nasal spray in 15 ml vials. Isofra (Framycetin) refers to aminoglycosides, which have a pronounced bactericidal effect. The antibiotic is actively used in clinical practice for the treatment of acute and chronic sinusitis, which are caused by aerobic bacteria (multiplying in an oxygenated environment) and anaerobes (developing in an oxygen-free space). However, the drug in clinical practice is used only intranasally, since it is recognized as a rather toxic compound (especially when it gets on the mucous membranes of the gastrointestinal tract).

Advantages and disadvantages

The main advantage is the short course of treatment, which is 3-7 days. However, this duration of therapy does not in any way affect the effectiveness of Isofra. This remedy can be used both for the treatment of adults and for the treatment of sinusitis that arose in childhood. At the same time, the antibiotic is almost not absorbed into the bloodstream, therefore it does not affect the functioning of the liver, stomach and intestines, does not cause a decrease in immunity and dysbiosis, and this allows the drug to be assigned a high place in the safety review.

The disadvantages of using Isofra include the fact that this agent does not affect pneumococci and streptococci, which are often the causative agents of prolonged sinusitis. Therefore, if symptoms do not improve after a week of use, another antibacterial drug will have to be prescribed. The cost of the medicine is 250 rubles.

An overview of antibiotics for children

At the moment, in Russia, a large number of antibiotics can be bought without a prescription. People used to think of antibacterial drugs as drugs that help with almost any disease, but this is not the case. Antibiotics are really effective only when the disease is provoked by bacteria, with the viral origin of the pathology, such drugs can only aggravate the child's condition, just as in the case of a disease caused by protozoa, for example, with amoebic dysentery.

Antibiotics for children can be used only if they are prescribed by a doctor after all the necessary examinations. In this case, the doctor must take into account the individual characteristics of the organism, the nature of the course of the disease, as well as all the available indications and contraindications. It is advisable to prescribe antibacterial drugs that do not affect intestinal motility and the normal flora of the body.

Cephalexin

Popularity rating: 4.9

An antibiotic from the group of beta-lactams, namely, it belongs to cephalosporins. Cephalexin is available in the form of 0.5 g capsules, 16 pieces per package. The drug has a pronounced bactericidal effect (destroys microorganisms). It is often used for inflammatory diseases of the upper respiratory tract, urinary system, skin and subcutaneous fat, ENT organs, and the musculoskeletal system. Its use is possible already from the neonatal period, however, the course and dosages are selected individually, taking into account the age and weight of the child. This approval for the use of the drug in neonates significantly improves the safety overview of the drug.

Advantages and disadvantages

The advantage of Cephalexin is its low price, which today is 65 rubles. It can be used already from the first month of a child's life, even with prolonged and severe infections. At the same time, you do not need to take the drug too often – 1-2 capsules a day are enough. Cephalexin has a pronounced effect on a wide range of bacteria, inhibiting their reproduction. It can be used as a first-line drug for pneumonia. It is one of the few cephalosporins that are given in capsules rather than injections.

The disadvantages can be possible side effects (dyspeptic phenomena: diarrhea, vomiting, nausea, flatulence) and allergic reactions. It should be used with caution for the treatment of premature infants with a burdened allergic history.

Clarithromycin

Popularity rating: 4.9

Clarithromycin is an antibacterial drug that belongs to the macrolide family. The antibiotic has a mild bacteriostatic effect, so it is often used for long-term infections of the upper respiratory tract, rhinitis, otitis media, sinusitis and sinusitis. It is produced in the form of tablets and capsules of 0.25 and 0.5 g. Clarithromycin inhibits the multiplication of pyogenic cocci, mycobacteria and Helicobacter pylori infection, therefore it is often used to treat stomach ulcers.

Advantages and disadvantages

The main advantage of Clarithromycin, like other antibacterial drugs from the macrolide group, is the minimal possibility of side effects. Therefore, the drug can be used already in the first year of a baby's life. Another advantage is that a course of treatment from 6 to 10 days is enough, while 2 capsules are prescribed per day. Rapid absorption and long half-life provides an effective action and achievement of a therapeutic effect in a short time. The price of an antibiotic is average and amounts to 230 rubles.

The disadvantages of Clarithromycin can be called low activity compared to other antibiotics (for example, from the group of cephalosporins). Therefore, in case of ineffectiveness or in the presence of a mixed infection, it is necessary to combine this drug with other antibacterial drugs. This may slightly reduce its effectiveness, but it increases its safety.

Lincomycin hydrochloride

Popularity rating: 4.8

Lincomycin hydrochloride is classified as an antibiotic from the lincosamide group. It can have both bactericidal and bacteriostatic effects on a large number of different microorganisms. Lincomycin hydrochloride is available in the form of a solution for injection and in capsules of 0.25 g. It is used for inflammatory processes of the skin, upper and lower respiratory tract, bones and joints, heart and blood vessels. The drug is rapidly absorbed from the gastrointestinal tract, and the maximum concentration is reached within a few hours. Actively affects the coccal flora, bacilli and other types of microorganisms.

Advantages and disadvantages

The advantage is the rapid absorption and action of the drug, as well as possible bacteriostatic and bactericidal effects in relation to many groups of microorganisms. The antibiotic is inexpensive, today it can be purchased at a price of 50 rubles.

Lincomycin hydrochloride has disadvantages and there are many of them. The antibiotic can only be used from 6 years of age. It should be prescribed with caution if the patient has chronic diseases of the digestive system, cardiomyopathy and allergic reactions. Lincomycin can lead to the development of dysbiosis and fungal infections of the skin and mucous membranes, therefore it is recommended to use supportive therapy. The combined balance of advantages and disadvantages allows lincomycin to maintain stable, mid-range broad-spectrum antibiotics.

Roxithromycin

Popularity rating: 4.7

It is an antibiotic from the macrolide group that is often used in pediatrics. Roxithromycin is available in the form of tablets of 0.15 g, 10 pieces per pack. It is classified as a broad-spectrum antibacterial drug, so it has found wide practical application. It is used to treat inflammatory diseases of the skin, upper respiratory tract, urinary system, ENT organs, bones. Roxithromycin is also used in the treatment of childhood infections caused by bacteria, namely scarlet fever, whooping cough, diphtheria. Often used for the prevention of infectious myocarditis during dental procedures.

Advantages and disadvantages

The advantage that increases the rating is the mild bacteriostatic effect, which mainly applies only to pathogenic microorganisms. At the same time, the normal intestinal microflora practically does not suffer, so dysbiosis and concomitant fungal infections are rare. Roxithromycin almost never causes allergic reactions. The drug is rapidly absorbed from the gastrointestinal tract and does not require frequent administration. The price of an antibiotic is quite low and amounts to 140 rubles.

Among the disadvantages of Roxithromycin, one can single out a negative effect on the enzymatic activity of the liver, therefore, an antibiotic should not be prescribed for dysfunction of this gland. Not recommended for infants under 2 months of age.

Furadonin

Popularity rating: 4.6

Furadonin (Nitrofurantoin) is a drug with a pronounced antimicrobial activity, which belongs to the class of nitrofuran derivatives. Actively inhibits the growth of bacteria by inhibiting the synthesis of RNA and DNA. The most common prescription of Furadonin in urology, due to its bacteriostatic action, it is used even for long-term urinary tract infections (pyelonephritis, cystitis, urethritis). It is produced in the form of tablets, which must be taken 2-3 times a day (as recommended by a doctor).

Advantages and disadvantages

The main advantage of Furadonin is that pathogens of urinary tract infections practically do not develop resistance (resistance) to this drug, this increases the effectiveness with prolonged use. Therefore, it can be taken as part of a comprehensive treatment that includes several courses. It is rapidly absorbed in the stomach, enters the blood plasma and binds to proteins, and then begins to act on the nephrons in the kidneys. The price of the antibiotic is low and amounts to 75 rubles.

The disadvantage is the fact that Furadonin can be used only from the age of 12, before that – according to indications and with caution. But in this case, it is completely replaceable with furagin. The drug can affect the function of the liver and the gastrointestinal tract in general, sometimes causes allergic reactions, neurotic disorders and dyspepsia.

Overview of broad spectrum antibiotics

Many inflammatory diseases are caused by bacteria, so the prescription of antibiotics in this case is the primary measure of etiotropic treatment (aimed at the cause of the disease). To prescribe the most effective antibacterial drug, you need to take the patient's material and make a sowing, and then determine the sensitivity of bacteria to certain drugs. However, such an analysis can be done from several days to several weeks, and the patient sometimes needs antibiotic therapy already at the time of seeking medical help.

For these purposes, broad-spectrum antibiotics are used. Their essence lies in the fact that they can act on a large number of species of bacteria and inhibit their growth. Consider an overview of the most popular drugs.

Wilprafen Solutab

Popularity rating: 4.9

This is an antibacterial drug that belongs to the last generation from the macrolide group. It is produced in the form of dispersed tablets, 10 pieces in a pack with a dosage of 1 g. Vilprafen Solutab (Josamycin) in small doses inhibits the growth of bacteria, that is, it has a bacteriostatic effect. But in large doses, this antibiotic acts as a typical bactericidal agent (destroys microorganisms). It is used to treat many diseases: infections of the upper and lower respiratory tract, genitourinary system, ENT organs, skin, sometimes it is used for gastritis, which is caused by the effects of Helicobacter pylori.

Advantages and disadvantages

The advantage of this drug is that it practically does not affect the intestinal microflora, does not cause dysbiosis. It has a long-lasting effect due to its long half-life. It is rapidly absorbed in the gastrointestinal tract, and the maximum concentration is reached in the blood within an hour. It is indicated for the treatment of many infections.

The disadvantage is the fact that Vilprafen Solutab crosses the placenta and can be excreted in milk during the period when lactation occurs. The antibiotic has a fairly high price, which today is 630 rubles.

Zinforo

Popularity rating: 4.9

Zinforo (Cefarolina fosamil) is an antibiotic of the fifth, last generation from a number of cephalosporins, which has a bactericidal effect. The antibiotic inhibits (suppresses) the growth of both gram-negative and gram-positive bacteria. Affects microorganisms that reproduce in oxygen and anoxic environments (aerobes and anaerobes). It can be used in some inflammatory processes that are caused by bacteria, namely in the pathology of the skin, upper and lower respiratory tract.

It is quickly enough absorbed, slowly excreted. It does not affect erythrocytes and hematopoiesis, it can have a rather strong effect on the gastrointestinal tract (suppresses normal microflora). It is produced in the form of a powder of 0.6 g in a vial, it must be diluted with saline before administration.

Advantages and disadvantages

The advantage of the drug is its high efficiency – usually just a few injections are enough to achieve a therapeutic effect. It can be used in inflammatory diseases when there are phenomena of mixed infection (caused by several infections).

However, the antibiotic can interfere with the functioning of the gastrointestinal tract, disrupting basic liver functions. The drug has a high price, Zinforo is not sold in all pharmacies, sometimes it is quite difficult to get it. It should be used with caution during pregnancy, lactation, in childhood. Like all antibiotics of the cephalosporin series, this drug does not have a tablet or encapsulated form – the drug is used only in the form of injections. This fact can also sufficiently 'downgrade' the drug's rating, despite its modernity and high efficiency.

Inwanz

Popularity rating: 4.8

Invanz (Ertapenem) is an antibacterial drug from the carbapenem group, which belongs to the latest generation of broad-spectrum antibiotics. It is produced in the form of a lyophysilate for injection, 20 ml each, with one bottle containing 1 g of active ingredient. It is used for peritonitis, infectious complications of abortion, pneumonia and other inflammatory diseases of the respiratory tract. Often, Invanz is prescribed for severe purulent inflammation of the skin and subcutaneous fat, meningitis, encephalitis and sepsis. Invanz has a pronounced bactericidal effect against many microorganisms.

Advantages and disadvantages

Invanz is rapidly absorbed and begins to act on microorganisms – it is administered intramuscularly or intravenously. Often it has a pronounced and rapid effect even with severe bacterial infections (septicemia, long-term pyelonephritis). May act on gram-positive and gram-negative aerobic and anaerobic bacilli and cocci. This antibiotic rightfully occupies a high position in the review – after all, it replaced such powerful drugs as Tienam and Meronem, and sometimes difficult patients can only 'rely' on such drugs.

The disadvantages of this antibiotic include frequent side effects that occur during the use of the drug. In 2-3% it causes dyspeptic disorders (nausea, vomiting, diarrhea), sometimes affects the central nervous system, provoking headaches, dizziness, visual and hearing impairments. It has not been clarified how Inwanz affects the intrauterine development of the fetus, therefore it can be used during pregnancy only in cases where the benefits outweigh the possible negative consequences. The price of the drug is high and amounts to 1,700 rubles.

Cubicin

Popularity rating: 4.8

Cubicin (Daptomycin) is available as a lyophilisate for injection at 0.35 or 0.5 g in a vial. This antibiotic belongs to the latest generation of lipopeptides (cyclic). Acts mainly on gram-positive bacterial flora, has less effect on gram-negative bacteria. Often used for infections that are caused by antibiotic-resistant Staphylococcus aureus. Prescribed, for example, in inflammatory processes of the skin and subcutaneous fat, postoperative purulent complications (including myocarditis and endocarditis), sepsis.

Advantages and disadvantages

The main advantage of Cubicin is its pronounced bactericidal effect, which develops 2-3 days after the start of therapy. In this case, a sufficient therapeutic effect is immediately achieved, and in the future it is supported by additionally administered doses of the drug. Antibiotics rarely cause side effects.

Therefore, the drug is indicated for septic conditions, because in the presence of a high concentration of pathogens in the blood, bactericidal antibiotics cannot be used: the destruction of a large number of microbes in the blood will lead to the release of their antigens and pathogenic factors into the blood, which can cause an infectious and toxic shock. Therefore, the bacteriostatic action of Cubicin allowed it to be assigned a place in the safety review.

The disadvantages are that Cubicin must be taken within 10-14 days. As a result of active suppression of the normal microflora of the body, complications such as fungal infections of the skin and urinary tract, headaches and neurotic disorders can develop. The price is high and amounts to 4900 rubles. It is not recommended to use it under the age of 18, during pregnancy, during lactation, and also after 65 years, especially if there are chronic diseases of the gastrointestinal tract, including the liver.

Maxipim

Popularity rating: 4.7

Maxipim (Cefipim) is an antibiotic from the 4th generation cephalosporin group. It is produced in the form of a powder in bottles of 1 g and 0.5 g. Before intravenous or intramuscular administration, it must be dissolved in saline or local anesthetics. The drug has a strong bactericidal effect, the maximum concentration in blood plasma is reached after 2-3 days. The half-life and half-life are long, so 1-2 injections per day are sufficient. Maxipim is used to treat bacterial infections of the upper respiratory tract, urinary system, genitals, skin and generalized processes (speticemia, septicopyemia).

Advantages and disadvantages

The advantages of Maxipim include its high speed of action, as well as the fact that there is no need to inject more than 2 times a day. At the same time, Maxipim acts on a large number of various microorganisms that often cause hospital and out-of-hospital infections. The antibiotic can be used in childhood, but this must be done with caution and only under the supervision of a doctor. Another plus is the low price, which is 320 rubles.

The disadvantages include a negative effect on the intestinal microflora. That is why it is always necessary to prescribe additional therapy, which is aimed at reducing the risk of developing dysbiosis. Maxipim is not recommended for use during pregnancy. As with other cephalosporins, the popularity rating can be lowered by the lack of oral forms (in the form of tablets and capsules for oral administration).

The popularity rating is based on the analysis of demand data from the wordstat.yandex.ru service.

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Attention! This rating is subjective and does not constitute an advertisement and does not serve as a purchase guide. Before buying, you need to consult with a specialist.