13 best venotonics for varicose veins

Review of the best according to the editorial board. On the selection criteria. This material is subjective and does not constitute advertising and does not serve as a purchase guide. Before buying, you need to consult with a specialist.

The use of venotonics is an important point in the successful treatment of varicose veins. Against the background of the use of such drugs, there is a decrease in unpleasant symptoms: pain, swelling, severity. In pharmacies, venotonics are presented in a wide range. Sometimes they are also called phlebotonics or venoprotectors.

Each of them has its own degree of effectiveness. But their common task is to increase the tone of the vascular walls and reduce capillary permeability. Venotonics are taken orally or used externally. They may contain flavanoids, rutosides, or other substances. Our experts conducted a study and ranked the best of them.

Rating of the best venotonics for varicose veins

Nomination a place Name of product price
The best venotonics for varicose veins based on flavanoids 1 Detralex 1 350 rub.
2 Phlebodia RUB 1,878
3 Vasoket 506 RUB
4 Venarus RUB 933
5 Phlebaven 597 r
6 Antistax RUB 1,750
7 Venozol 249 r
The best venotonic-rutosides for varicose veins 1 Troxevasin 390 RUB
2 Venoruton RUB 1,024
3 Ascorutin 36 RUB
The best external venotonics for varicose veins 1 Dr. Theiss Venen gel 240 RUB
2 Venitan 252 RUB
3 Herbion Aesculus 107 RUB

The best venotonics for varicose veins based on flavanoids

These are biologically active compounds of plant origin. Venotonics with flavonoids successfully eliminate the initial signs of varicose veins: discoloration of the skin, itching or burning, ulceration, pain, fatigue, heaviness in the legs.


Rating: 4.9


The first place in the ranking is occupied by the French drug Detralex. It can be purchased as a suspension or film-coated tablets. They can contain 500 or 1000 mg of a purified micronized flavanoid fraction, which includes 90% diosmin and 10% hesperidin.

With varicose veins, Detralex is taken 1 tablet (1000 mg) or 1 sachet (1000 mg) 1 time per day. It is preferable to do this in the morning, during breakfast. Some phlebologists prescribe the drug twice a day, 1 tablet (500 mg). The therapeutic course is continued for 3-6 months. In some cases, treatment can continue throughout the year.

According to reviews, after 1 month of use, it is possible to forget about the heaviness and constant fatigue of the legs. And after 2 months, protruding veins are less striking. The most common side effects when taking this venotonic are gastrointestinal disturbances, but usually everything is far from critical. Our experts have included Detralex in the rating of the best, since this original drug is effective for varicose veins and is safe.


  • an original drug that has passed many tests;
  • contains diosmin and hesperidin;
  • guaranteed relieves of heaviness, pain, increases the tone of the veins.


  • digestive disorders are possible.


Rating: 4.8


Another French venotonic Phlebodia took the second position in the ranking. He has the only form of release – film-coated tablets. They contain 600 mg of the bioflavonoid diosmin. Phlebologists love this drug and often prescribe it to their patients with varicose veins. Phlebodia perfectly tones blood vessels and relieves inflammation.

With varicose veins, 1 tablet is prescribed per day. Take the medicine in the morning on an empty stomach. Treatment continues for 8 weeks. If the patient has forgotten to take the medicine one or more times, then the use of venotonic is continued according to the previous scheme without changing the dosage. Phlebodia is not used to treat children under the age of 18.

Patients in the reviews note that despite the rather impressive size of the tablets, they are swallowed without problems. For 2 months of use, the drug allows you to completely forget about pain in the legs, swelling and ugly protruding veins. Phlebodia deserves to be in the ranking, because it is well tolerated by patients and is an excellent preventive measure for varicose veins.


  • convenient to take;
  • provides lightness in the legs;
  • improves venous outflow;
  • good prevention of varicose veins.


  • may cause dyspepsia or headache.


Rating: 4.7


The third place in the ranking went to the German / Swiss drug Vasoket. It is considered a cheaper analogue of the venotonic Phlebodia. Vasoket is available in tablets containing 600 mg of diosmin. Thanks to this drug, the veins become less elastic and tone up. In addition, local blood circulation improves and inflammation is relieved.

Patients with varicose veins take the medicine 1 time per day, 1 tablet. Drink the prescribed dose in the morning before breakfast for 2 months. A repeated course is allowed to be done after an 8-12 week break. Vasoket is contraindicated in children under 18 years of age, as well as in people with individual intolerance to certain components of the drug.

Reviews about Vasoket are mostly positive. This drug is not as popular as Phlebodia, but no less effective. Patients note that Vasoket successfully relieves all the main symptoms of varicose veins. It is included in the rating because it rarely causes side reactions in patients and fully lives up to the manufacturer's promises.


  • dividing line tablets;
  • eliminates pain, heaviness, swelling;
  • does not cause stomach problems.


  • not sold in all pharmacies.


Rating: 4.6


The Russian counterpart of Detralex Venarus occupies the fourth position in the rating. This medication is available in film-coated tablets, which have different dosages and packaging. It contains diosmin and hesperidin. With regular use of Venarus, it is possible to reduce the elasticity of the veins and bring them into tone. Also, under the influence of this drug, congestion in the veins is eliminated.

It is supposed to take 2 tablets per day. The dose can be taken immediately or divided by 2 times. Drink Venarus while eating. Despite their size, the tablets can be swallowed quite easily, but you can use the dividing line if you wish. The course of treatment can be 3-4 months (up to 1 year).

In reviews, patients often compare Venarus and Detralex in terms of effectiveness. Opinions differ, but quite a few people believe that the Russian drug is in no way inferior to the French one, but noticeably wins in price. Our experts included it in the rating because Venarus is a quality generic that rarely causes side effects. At the same time, it successfully removes pain and heaviness in the legs, which often occur with varicose veins.


  • diosmin and hesperidin in the composition;
  • tablets are easy to swallow;
  • in terms of effectiveness, it is not inferior to the original drug;
  • sold in any pharmacy.


  • can cause diarrhea, dyspepsia, nausea, vomiting.


Rating: 4.5


In fifth place was another Russian drug Flebaven. It is also a generic drug for Detralex, but less popular than Venarus. This venotonic is produced in one dosage – 500 mg each. Contains diosmin and hesperidin. With regular use, it reduces the severity of symptoms of chronic varicose veins, which are of an organic or functional nature.

Phlebaven is taken internally. The daily dose should be 1000 mg of the flavanoid fraction. With this in mind, Flebaven is taken twice a day, 1 tablet. This is done during lunch and dinner. The tablets are quite large, but usually swallowed without problems.

According to reviews, this is a great budget alternative to Detralex. The first noticeable improvements are visible after 1-2 weeks of use. Our experts have included this venotonic in the rating of the best, because it tones the veins well, protects the venous walls, and also helps better blood circulation in the extremities. Moreover, it causes no more side effects than an imported drug.


  • effective composition;
  • efficiency;
  • attractive price.


  • possible problems with the gastrointestinal tract.


Rating: 4.5


The sixth place in the rating is occupied by Antistax. Its manufacturer is Switzerland / France. This venotonic is available in capsules. The dry extract of red grape leaves is responsible for the therapeutic effect here. It contains quercetin and isoquercetin (flavanoids). It is widely used for the treatment and prevention of varicose veins.

Patients use Antistax 1 time per day, 2 capsules. Do this in the morning before breakfast. Depending on the symptoms, the dose is increased to 4 capsules per day. It is not recommended to chew the medicine. The capsule is swallowed whole and washed down with a glass of clean water without gases. The therapeutic course is designed for 12 weeks. Antistax is approved for use from the age of 18.

Patients in the reviews note that the capsules are easily swallowed, and the gastrointestinal tract reacts to them much better than to diosmin containing. However, experienced varicose veins report that this venotonic is weaker and more suitable for prevention or at the initial stage of the disease. Nevertheless, Antistas entered the rating of the best, since it has a natural composition, quite effectively normalizes vascular permeability, and also slows down the formation of edema and reduces existing ones.


  • phytopreparation;
  • practically does not cause side effects;
  • moderate venotonic effect.


  • the capsule shell contains sodium lauryl sulfate.


Rating: 4.4


Closes the rating of the best venotonics based on flavonoid dietary supplements Venozol. It is produced in capsules and contains the following components: diosmin (270 mg), chestnut extract, hesperidin (30 mg), hazelnut extract, dihydroquercetin (antioxidant). The components of the complex increase the tone and strengthen the walls of blood vessels, and also normalize venous circulation.

Venozol is prescribed for varicose veins in adults and children from 14 years of age, 1 capsule 1-2 times a day, together with meals. Duration of admission is 6-8 weeks. This venotonic is contraindicated for pregnant and lactating women. The size of the capsules themselves is small, so it is not difficult to take them, they do not get stuck in the throat.

Many people praise Venozol in their reviews. With so many components in the composition, it has an attractive price. This venotonic is present in the rating, since, although it belongs to dietary supplements, it is not inferior in effectiveness to original drugs. However, the content of diosmin and hesperidin is relatively low here, so this agent should rather be considered as a prophylactic.


  • combined composition;
  • convenient size of capsules;
  • clear application scheme;
  • relieves heaviness, pain in the legs.


  • relatively low content of diosmin and hesperidin.

The best venotonic-rutosides for varicose veins

Rutosides are glycosides of the flavanoid quercetin. They belong to the group of vitamin P. In their natural environment, they contain citrus fruits, black currants, dandelions, buckwheat.


Rating: 4.9


Bulgarian venotonic Troxevasin occupies the first position in the rating. Its active ingredient is troxerutin (a semi-synthetic derivative of rutin). For oral use, it is sold in capsules only. Troxerutin, acting directly on the blood vessels, eliminates pain, heaviness, cramps and swelling.

The Troxevasin capsule is swallowed whole and washed down with a glass of gas-free water. Initially, patients are advised to take 300 mg (1 capsule) of troxerutin 3 times a day. Positive dynamics occurs after 2 weeks. Then the therapy is continued, resorting to the same dosage, or reduced to the minimum maintenance. Most often, treatment is continued for 3-4 weeks.

Some in the reviews call Troxevasin a 'veteran' in the fight against varicose veins, but at the same time consider it quite effective. Patients often combine capsules and gel with troxerutin. Our experts included this venotonic in the rating of the best, because although it acts slowly, it noticeably improves the condition of the veins with varicose veins during the course of treatment.


  • non-congested, but effective composition;
  • minimum of side reactions;
  • well eliminates swelling, pain, heaviness.


  • begins to act slowly.


Rating: 4.8


The second place in the rating is occupied by the Indian venotonic Venoruton. The active substance is hydroxyethylrutosides 300 mg. It is a derivative of rutin that has a therapeutic effect directly on the vessels. Thanks to Venoruton, they are toned and strengthened. This venotonic is produced in capsules.

Patients use Venoruton together with meals. The capsules are not chewed and washed down with clean water. During the first two weeks, Venoruton is taken 1 capsule up to three times a day (no more than 3 capsules). Further therapy is continued for 8-12 weeks, using a maintenance dosage, or treatment is completely stopped.

According to reviews, Venoruton is quite effective for varicose veins and practically does not cause side reactions. This venotonic is deservedly in the ranking of the best, since with course use it noticeably reduces the severity of puffiness, pain, heaviness or ulceration.


  • effective active component of the composition;
  • good tolerance;
  • the capsules are easy to swallow.


  • only suitable for treating adults.


Rating: 4.7


As part of complex therapy for varicose veins, Ascorutin can be prescribed. It closes the rating of the best venotonic-rutosides. It is produced by many Russian manufacturers. Along with routine, it contains ascorbic acid. Thanks to these substances, Ascorutin eliminates increased capillary permeability, strengthens the vascular wall, reduces its swelling and eliminates the inflammatory process.

Take 1 tablet of Ascorutin orally 2-3 times a day during or after the main meals. The therapeutic course is on average 2-3 weeks. It comes in small standard tablets. They have a pleasant sour taste, reminiscent of ascorbic acid without sugar.

There are extremely positive reviews about Askorutin. Many people like these vitamins and their affordable price. This remedy cannot be called the main venotonic, but as a complex therapy, it deservedly can be in the ranking of the best. If you follow the instructions, then Ascorutin will not only improve the state of blood vessels with varicose veins, but also increase immunity.


  • pleasant taste;
  • has a tonic effect on the body;
  • reduces swelling, inflammation;
  • has an affordable cost.


  • as an independent venotonic is rather weak.

The best external venotonics for varicose veins

Phlebologists often prescribe to their patients with varicose veins herbal venotonics for external use.

Dr. Theiss Venen gel

Rating: 4.9


The first place in the rating is occupied by the German plant-based venotonic Venen gel. Each 100 g of the product contains 400 mg of a thick extract of calendula flowers and 3 g of a liquid extract of horse chestnut seeds. Venen gel reduces capillary permeability, tones up the vascular walls, eliminates edema and inflammation.

Venotonic for varicose veins is applied 2 times a day (morning and evening) with a thin layer on the pathological focus and rubbed with light massaging movements. The drug has a light gel consistency and a pleasant smell. After spreading over the skin, it is quickly absorbed and leaves no residue. After application, a slight chill is felt.

According to reviews, Venen gel fulfills all the promises stated by the manufacturer. It relieves heaviness and fatigue from the legs, and with regular use, bulging varicose veins become less noticeable. This herbal venotonic deservedly appeared in the rating of the best, since it effectively fights varicose veins and does it gently, without pronounced side reactions.


  • vegetable composition;
  • cooling effect;
  • non-sticky, quickly absorbed;
  • eliminates swelling and pain.


  • allergic reactions are possible.


Rating: 4.8


Another German gel for varicose veins Venitan took the second position in the ranking. The active substance of this herbal venotonic is β-escin (a mixture of triterpene saponins) 10 mg. It contains horse chestnut seeds. Escin relieves inflammation, reduces venous congestion, prevents the appearance of puffiness.

Venitan gel is applied on the skin of pathological foci with a thin layer and gently rubbed. It is best to avoid massaging movements during application. It is recommended to distribute the gel over problem areas 2-3 times a day. With varicose veins of the lower extremities, the effect will be many times better if you use an elastic bandage or wear special tightening tights.

In the reviews, patients report that Venitan is quite effective, but unpleasant to use, since it is very sticky and absorbed for a long time. But nevertheless, our experts included it in the rating of the best, since Venitan relieves swelling, severity and quickly resolves hematomas. Moreover, it is allowed to be used during pregnancy and lactation.


  • natural composition;
  • suitable for pregnant and lactating women;
  • quickly relieves leg fatigue;
  • relieves pain, relieves edema.


  • sticky, specific smell.

Herbion Aesculus

Rating: 4.7


Closes the rating of the best external venotonic gel Gerbion Esculus, produced in Slovenia. Each gram of this product contains 350 mg of liquid extract of horse chestnut seeds and 20 mg of liquid extract of sweet clover herb. Both components complement each other's action and intensely tone the blood vessels.

Gerbion Esclus is distributed over the skin in the area of ​​pathological foci with a thin layer up to four times a day. You should not rub in the product. In the treatment of chronic varicose veins, Esculus is sometimes used for compresses. In pediatric practice, it is not recommended to use this venotonic on extensive skin surfaces, as well as for a long time.

According to the reviews of patients, it becomes clear that after the application of Aesculus, a slight tingling is felt on the skin, which quickly passes. The gel is absorbed quickly without leaving a sticky film. The drug effectively eliminates the feeling of heaviness and pain in the legs, significantly reduces swelling. The effect is especially noticeable after a full working day on your feet. Immediately after the application of the gel, relief comes and the pain in the legs recedes.


  • natural composition;
  • pleasant consistency;
  • absorbs quickly, leaves no sticky film;
  • effectively relieves fatigue and swelling.


  • harsh odor.

Attention! This rating is subjective and does not constitute an advertisement and does not serve as a purchase guide. Before buying, you need to consult with a specialist.

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