The 7 Best Diet Pills

Review of the best according to the editors. About the selection criteria. The the material is subjective, is not advertising and is not serves as a guide to the purchase. Before purchase is needed consultation with a specialist.

The eternal question haunting our contemporaries. regardless sex: “What would you eat to lose weight?”. Human organism, like all other mammals, formed under conditions when hunger was the norm rather than the exception, and those who survived relatively well-fed times accumulated fat more efficiently than the rest. They left offspring, which in a sudden food the abundance began to plump rapidly: according to doctors in our In the country, 59.2% of all adults are overweight.

Theoretically, everyone knows the prescription for losing weight: eat less and more move. In practice, this is not always the case, and go “magic pills”.

By ranking the best diet pills, we considered only funds officially registered in Russia as a dietary supplement or medicine. We have not deliberately included him “Chinese” or “Thai pills” with an unknown composition and medicines that can not be obtained through official means.

When choosing a tool that promotes weight loss, you need to remember that in medicine there are clear criteria for the effectiveness of weight loss and they far from widely publicized 7 – 10 kilograms per week. National clinical guidelines for the treatment of obesity are called safe loss of 5 – 10% of the initial weight per month, which is practice is not more than 3 kg per week.

And before moving on to the actual rating, we recall that no pills will help if the weight is medical a norm that does not always comply with modern standards beauty. A body mass index of 18.5 to 24.99 is considered normal. BMI is calculated by the formula: weight in kg / (height in m) 2

Comparison Chart of Different Weight Loss Means

Slimming Medicines

Bad weight loss

Slimming Tea

active substance

synthetic

synthetic, natural extracts

natural herbs

weight loss mechanisms

decreased appetite, normalization of metabolism

decreased appetite

metabolism normalization

dehydration

have clinical trials been conducted

Yes

more often than not

not

side effects

there is

are possible

there is

addictive

not

not

Yes

yo-yo effect (quick return to original weight) after end of application

available

available

Yes

Excess weight can be not only the result of immoderate nutrition, but also a consequence of serious diseases:

  1. polycystic ovary syndrome;
  2. Cushing’s syndrome;
  3. hypothyroidism;
  4. dysfunction of the hypothalamus;
  5. hyperprolactinemia, etc.

Therefore, when it’s not just about being overweight, but about Obesity, before you prescribe a pill you need to consult to the doctor. You can only take weight loss medications by making sure that the reason for overweight is precisely in the features of lifestyle.

Rating of the best diet pills

Nomination a place Name of product price
The best medicine for weight loss 1 Sibutramine 1590 rub.
2 Orlistat 681 rub
3 Metformin 92 rub
The best dietary supplements for weight loss 1 Chromium Picolinate 931 rub
2 Garcinia Cambodian 347 rub
3 Alpha lipoic acid 650 rub
4 L-carnitine 301 rub

The best medicine for weight loss

In this section we have collected medicines designed to help combat weight loss. All these diet pills are prescription because it’s pretty tough interfere with the work of nerve centers or metabolism, which is why Serious side effects may appear. Therefore most often similar medications are recommended for people with severe obesity (BMI > 30) в ситуациях, когда диета и спорт не помогают.

On the other hand, unlike dietary supplements, for the registration of which confirming the effectiveness of the action is not necessary, all weight loss medications have confirmed their clinical trial efficacy – without registration medication is not possible.

Sibutramine

Rating: 4.9

Reduxin

Trade names: Reduxin, Goldline.

Sibutramine is ideal for people who honestly try to comply. diet, but can not withstand constant hunger. Acting directly to the saturation center in the brain, these pills help to eat up in small portions. And since in the process serotonin and adrenaline receptors are activated, an added bonus is increased activity and less need for sleep. True, this coin has a downside: increased activity can easily turn into anxiety, decreased the need for sleep to turn into insomnia, and the impact on adrenaline receptors – provoke an uncontrolled increase pressure. Sibutramine increases the load on the heart and blood vessels: blood pressure in on average increases by 1 – 3 mm. Hg. Art., and the pulse for 3 – 7 beats per minute. That is why it is banned in European countries Union.

Many people who have used this medication complain of complete loss of pleasure in eating. On the one hand, it helped them reduce weight, on the other hand, such sensations are very subjectively transferred heavy.

Often people taking the medicine complain of a dry mouth, complete lack of appetite, a change in taste sensitivity, constipation. Among other side effects are traditional allergic reactions, headache, transient increase in hepatic enzymes “(transaminases) in the blood.

Judging by reviews and publications in medical journals, sibutramine works great “at short distances” from a month to three, then they get used to it and weight loss slows down.

Taking medication for more than a year in a row is not recommended, the safety of such a long-term use is simply no one studied.

You need to start with a dose of 10 mg once a day, if during month failed to lose 5% of the initial body weight, It is recommended to switch to a dosage of 15 mg, if it turns out ineffective, further experiments need to be stopped.

Sibutramine is categorically not suitable for people suffering “binjami” – bouts of uncontrolled overeating, when a person comes to life in an empty refrigerator with heaviness in the stomach and confusion: why, in fact, did he eat all this? Such situations are not as rare as average people think, and require work with a psychologist. Control the appetite of people who eat not because they are hungry, but because of stress, it is useless.

The list of contraindications to the use of the drug is quite long:

  1. age up to 18 years;
  2. pregnancy and lactation;
  3. obesity is caused not by overeating, but by a disease (hypothyroidism, polycystic ovary syndrome, Itsenko-Cushing’s syndrome and others);
  4. IHD, arrhythmias, heart failure at any stage;
  5. Blood pressure above 145/90;
  6. thyrotoxicosis;
  7. pheochromocytoma;
  8. angle-closure glaucoma;
  9. benign prostatic hyperplasia;
  10. renal or liver failure;
  11. alcohol, drug or drug addiction.

Sibutramine should not be taken with antidepressants, other diet pills and sleep aids based on tryptophan.

Advantages

  • reduces excessive appetite,
  • helps to reduce weight
  • increases activity.

disadvantages

  • gives a load on the vessels and heart.

Orlistat

Rating: 4.8

Xenalten

Trade Names: Orliksen, Xenalten, Listata, Xenical, Orlimax.

If sibutramine acts on the brain, “cutting off” interest in food and the pleasure of its absorption, then orlistat works at the level of intestines, blocking enzymes that break down fats. Large molecules fat are not able to pass through the wall of the intestine, and leave the body along with other undigested food debris. Insofar as fat is the most high-calorie part of the diet, the number of calories acquired decreases and a person loses weight, not limiting himself in loved ones products.

That is the theory. In practice, those taking orlistat you have to control the contents of the plate in the most stringent way. Because undigested fats irritate the intestinal wall. And barely their number in the dish will exceed a certain minimum, for each his own, the intestines begin to contract uncontrollably, which forces sorry for naturalism, run to the toilet. Naturally, like embarrassing situations force you to limit fat in food, which means that who claims that taking orlistat can not change food habits, at least they are cunning.

By the way, this effect must be borne in mind by women, taking contraceptives – due to the fact that the intestines released faster, hormones do not have time to fully absorb that reduces the effectiveness of the drug.

Orlistat, on the other hand, can probably be advised to people suffering from eating disorders, since fat absorption really decreases and calories during overeating people will get less. True, the thrill will also be guaranteed.

It is with intestinal irritation that undigested fats are caused most of the side effects that occur when taking orlistat:

  1. gas exhaustion, often with some content intestines;
  2. sudden strong urge to defecate;
  3. loose stools;
  4. abdominal pain.

Other adverse events may include allergic reactions and problems associated with a decrease in the effectiveness of drugs that a person takes constantly (antihypertensive, contraceptives, antiepileptic and so on).

Of the positive aspects, it should be noted that tablets are not only help to reduce weight, but also normalize cholesterol and triglycerides in the blood. In addition, poison them – that is, create in the body is too high a dosage – almost impossible: the active substance is not absorbed inward, remaining in the lumen intestines. Therefore, orlistat has a minimum of contraindications:

  1. malabsorption syndrome (malabsorption in the intestines or other component of food);
  2. cholestasis;
  3. pregnancy, lactation, childhood – in these categories No one has tested the safety of people.

Orlistat should not be taken simultaneously with warfarin and others blood coagulation agents, or simultaneously with cyclosporine.

Use these diet pills three times a day during food Time. If in three months the weight has decreased by no more than 5% of initial, further use of the drug should be discontinued. The duration of the course is not limited to instructions. but need note that absorption is blocked along with fats and fat-soluble vitamins A, D, E, K, which are vital the body.

Advantages

  • few contraindications
  • normalizes the lipid composition of the blood,
  • makes you follow a diet.

disadvantages

  • extremely uncomfortable side effects.

Metformin

Rating: 4.7

Glucophage

Trade names: Glucophage, Siofor, Gliformin.

These pills were not originally developed for weight loss, but for correction of sugar level in patients with type 2 diabetes. But after several years of sales, it turned out that they contribute to active weight loss – and the drug began to be used, including for fighting overweight. And, despite the fact that formally decline weight in the instructions for use of metformin is not indicated, among показаний к применению есть ИМТ > 35, то есть ожирение, приwhich dramatically increases the risk of diabetes.

The main action of metformin is restoration of sensitivity organism to insulin. It is the insensitivity of cells to this a hormone that lowers blood glucose and causes type 2 diabetes.

The medicine works in several directions, and we will not give all the mechanisms of its influence on the body, limiting itself only important in the context of losing weight. It:

  1. decrease in the activity of absorption of carbohydrates in the intestine;
  2. transformation of glucose into lactic acid in the lumen intestines;
  3. activation of an enzyme called adenosine monophosphate activated protein kinase, which reduces glucose synthesis liver and activates the oxidation of fatty acids.

Translating from medical to understandable, metformin is not only reduces glucose intake from food, which indirectly reduces the amount received in calories, but also helps the body break down your own fat using energy as a source primarily fat stores, not glucose, the production of which in liver under the influence of the drug is reduced.

Metformin will be useful not only for those who already have a diagnosis type 2 diabetes, and especially people with sugar levels blood still remains within normal limits, but sensitivity to insulin is already broken and the level of this hormone in the body begins rise steadily. This condition is called prediabetes.

To detect it, you need to donate blood for analysis, including Calculation of CARO and HOMA-IR indices. Without going into unnecessary details let’s say that these indices are based on measurement correlation between the amount of insulin in the blood and glucose level on an empty stomach. Divide the circle to find out if such an analysis is needed. your waist to your hips. If the value is greater 0.85 for women or 0.9 for men – high risk of metabolic a syndrome which, among other symptoms, is manifested in violation body sensitivity to insulin.

There are other indications for the use of metformin, in addition to prediabetes:

  1. ИМТ>35;
  2. type 2 diabetes in blood relatives;
  3. past pregnancy diabetes;
  4. elevated blood triglycerides;
  5. arterial hypertension.

Take metformin as weight loss pills 850 mg first once a day, after 10 days – 2 times a day. The medicine does not cause an excessive decrease in blood sugar, but with a gradual increase in dosage is less likely the appearance of side effects from the gastrointestinal tract, such as nausea, a sharp decrease in appetite, abdominal pain, diarrhea.

Among other adverse events is a taste disorder, allergic skin rashes. Very rarely possible lactic acidosis – acidification of the body with lactic acid, which manifests itself as symptoms like weakness, muscle pain, drowsiness. In this case immediately stop taking the medicine and consult a doctor. To prevent this condition, you can not combine metformin with extremely strict diets – daily calories should be like minimum 1000 kcal. The likelihood of developing lactic acidosis with alcohol poisoning while taking metformin, therefore, it is strongly discouraged to abuse alcohol.

The drug is contraindicated in severe renal, hepatic and cardiovascular failure. Not recommended for pregnant since safety for the fetus has not been established. Can not take metformin 2 days before and 2 days after radiopaque studies using iodine preparations.

With prolonged use of metformin, vitamin absorption is reduced B12, therefore it is recommended to periodically use multivitamin drugs.

Advantages

  • prevents the development of type 2 diabetes as complications obesity.

disadvantages

  • side effects from the gastrointestinal tract.
  • the possibility of hypovitaminosis B12.

The best dietary supplements for weight loss

With all the benefits of weight loss drugs, they have one serious flaw: prescription. What in practice means various contraindications and the need to carefully control the state of the body in time to notice side effects. In this regard, biologically active additives at times safer.

On the other hand, to register, produce and to sell dietary supplements you only need to prove that the substances in it are available, do not harm health. There is no need to prove the benefits and effectiveness. Of course, when creating formulas, pharmacologists usually focus on the results of a certain amount of research but conduct clinical trials of the finished product, they are not required. therefore choosing diet pills from the number of dietary supplements, often to go by trial and error.

In addition, unlike drugs, dietary supplements for weight loss “by themselves themselves “are most often ineffective. They accelerate weight loss during diets or enhance fat burning during exercise or help to avoid “harmful” foods. But just eat diet pills, maintaining a familiar lifestyle, and really lose weight does not work.

Offering you the rating of the best OTC tablets for weight loss, we focused primarily on acting substances and their effect on the body. Listed in this section funds can be bought in ordinary pharmacies and in foreign Internet sites.

Chromium Picolinate

Rating: 4.5

CHROME PICOLINATE.jpg

Trade Names: Turboslim Chromium Picolinate Evalar, Solgar Chromium Picolinate, Nature’s Way, Chromium Picolinate.

Chromium is involved in the metabolism of fats and carbohydrates, stimulates insulin receptors, a deficiency of this trace element provokes the occurrence of insulin resistance. Chromium Picolinate Promotes reduce cravings for sweets, so it’s best for those who trying to get rid of sugar addiction. Especially good judging by the reviews, it reduces the “evening glitches.” True for To achieve this effect, you need to take pills at least for months.

Some studies have shown that chromium picolinate can help lower blood sugar and reduce symptoms Depression is no secret that this condition is often accompanied by overeating and gaining excess weight. But this data require further study.

Advantages

  • reduces cravings for sweets.

disadvantages

  • the effect manifests itself not earlier than after a month of use.

Garcinia Cambodian

Rating: 4.4

HARCINIA CAMBODIA.jpg

Trade Names: Garcinia Forte Evalar, Evalar Tropicana Slim Garcinia Chewable Tablets, Now Foods Garcinia 1000 mg, Natrol, Garcinia Cambogia 1000 mg.

Natural plant extract that prevents lipogenesis – fat deposition in cells. Promotes the oxidation of fats. Reduces hunger.

Against the background of a low-carb diet, it can provoke a sharp a decrease in blood glucose, so combine taking garcinia with “carbohydrate-free” is not worth it. Hypoglycemia is manifested by dizziness, general weakness, chills, aggressiveness. In this case, it’s better to immediately drink sweet tea or eat candy.

As with most other over-the-counter tablets, weight loss effect becomes noticeable no earlier than a month after start of reception.

Several years ago, information appeared that Garcinia may contribute to liver damage. But since this is a side effect found in a complex agent containing besides garcinia and other substances, there is no final opinion on this issue yet. IN in any case, use garcinia preparations for liver pathologies Not recommended.

Advantages

  • slows down the deposition of fat in the body,
  • stimulates the immune system.

disadvantages

  • possibly causing liver damage.

Alpha lipoic acid

Rating: 4.3

ALPHA-LIPOIC ACID.jpg

Trade Names: Thioctic Acid, Thioctacid, Berlition, Lipoic Acid Evalar, Doctor’s Best, Alpha-Lipoic Acid.

In Russia it is sold as a medicine (Thioctacid, Berlition), and as a dietary supplement (Evalar).

Originally designed for people with type 2 diabetes, for protect nerve cells and blood vessels from toxic effects excess glucose in the blood. In addition, she has a pronounced hepatoprotective effect – that is, it protects liver cells. IN as a means of losing weight, alpha lipoic acid is effective only subject to physical activity – in this case, it activates the breakdown of fat and its use as main source of energy. So lie on the couch and lose weight with these pills will not work, although periodically appears information that alpha lipoic acid reduces appetite and cravings for sweets due to the normalization of glucose metabolism.

Advantages

  • protects liver cells from harmful effects.

disadvantages

  • works like a fat burner only against the background of physical exercises.

L-carnitine

Rating: 4.2

Now Foods L-Carnitine. jpg

Rating: 4.2.

Trade Names: Elkar, L Carnitine Evalar, Now Foods L-Carnitine.

This tool is well known among bodybuilders – it helps cope with heavy physical exertion and by increasing training volume helps to “grow” muscles better. But besides of this, it also speeds up fat burning, helping to transport fats inside mitochondria – the “energy stations” of cells.

Like alpha lipoic acid, L-carnitine works effectively on losing weight only in combination with physical activity.

Advantages

  • stimulates muscle growth
  • protects myocardial cells from hypoxia.

disadvantages

  • It works only in combination with physical activity.

Diet Pills vs Diet Teas

The attentive reader must have noticed that our rating called the “7 best diet pills,” which is for sure excludes from it “slimming” teas popular among many girls. And there is a reason for this.

After studying the composition of the most popular teas for weight loss, we found there senna or other herbs with a strong laxative effect and herbs with diuretic action. Using similar means to lose weight impossible: weight loss is only due to intestinal contents and concomitant dehydration. Speaking of diet pills you can talk about the ratio of benefit and harm, then in the case of teas neither what benefits are we talking about: continuous bowel stimulation leads to the fact that he ceases to work independently, and diuretic herbs increase the burden on the kidneys, while long dehydration can even provoke renal failure. With constant loss of water through the intestines and kidneys electrolytes, especially potassium, are excreted from organisms which can cause night cramps and arrhythmias.

Moreover, all these risks are completely meaningless: literally for a few days after the end of tea, the body recovers water balance and, sorry for being rude, the number of poop in the guts, after which the balance arrow returns safely to its original values.

Many people think that teas are safer than pills because herbs are completely natural. Take a chance to recall that poisonous plants or mushrooms are also completely natural remedies. Side phenomena arising from the abuse of slimming teas we described above.


Attention! This rating is subjective, not advertising and does not serve as a guide to the purchase. Before the purchase consultation with a specialist is necessary.

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