8 best tinnitus drugs

Review of the best according to the editors. About the selection criteria. The the material is subjective, is not advertising and is not serves as a guide to the purchase. Before purchase is needed consultation with a specialist.

Tinnitus, or tinnitus, is a condition that can significantly worsen the quality of life, although at the same time the person does not experiencing no pain, and can move normally. But here his whole life, and especially in silence, sometimes passes under the influence of almost constant noise, and it is very painful. It is estimated that almost 40% of people sometimes feel tinnitus, 8% call it permanent, and every hundredth person almost constantly suffers from exhausting noise, which interferes not only at night, but also during the day.

The problem is most investigated in the USA, and there are 2 million patients with tinnitus are disabled, and 18 million patients treated for tinnitus of varying severity. Amazing that absolutely deaf patients who were born deaf never Do not complain about noise. It is also interesting that based on noise complaints it is impossible to make an accurate diagnosis of any disease (it does not is a pathognomonic symptom). It is clear that the vast most patients with noise have a certain loss hearing.

How to determine tinnitus? This is a condition in which sound felt in the ears or head, but no external acoustic no impact. What happens is this unpleasant, interfering sensation?

Varieties of noise

Tinnitus can be classified according to various parameters. For ENT doctors can conveniently distribute and classify noise, for example, by his reasons. There may be vascular noise caused by a lesion. structures of the outer and middle ear associated with muscle tension, and also peripheral and central types of noise.

In addition, noise can be objective and subjective. IN the first case, the noise really exists and can be heard doctor, and determine using diagnostic research methods. But subjective noise is the same tinnitus, a noise phantom. He only felt, but in reality it does not exist.

Objective noise is very rare and can be heard even to an outsider. An example is carotid-cavernous anastomosis, with flow-discharge of blood from one another basin in the cranial cavity, which causes characteristic noises. Normally, it should not be.

Noise can be on one side or on two, it can be periodic or permanent. Some patients excrete pulsating noise and monotonous, consisting of low frequencies or high, it can be very intense or weak.

Finally, noise may be the patient’s main complaint about see a doctor, or secondary. And it is very convenient for the doctor: distribute noise in three degrees of “importance”:

  1. the first degree is the absence of active complaints of noise, and this the complaint is opened, updated by the inquiring questions of the doctor, the patient does not complain on his own;
  2. second degree – when the patient complains, but considers the noise still not the main problem;
  3. finally, if the noise in the ears or in the head is a major complaint, which prevents him from living, and with him he came to the doctor – that’s about severe tinnitus.

Why is there noise and what are its sources?

A bit about the reasons

In the human body there really is something to make noise. May be sound from contraction of various muscles, from movement temporomandibular joint, and its ligaments, from blood flow to vessels of large and medium caliber. But usually in a healthy person all these sound phenomena are very well disguised, and not are determined. What are the most likely causes of noise development, who can hear another person, that is, an objective? Here they: this is arthrosis of the temporomandibular joint, a wide gap auditory tube, myoclonus muscle structures of the middle ear, its tumors, narrowing of arterial vessels, and their abnormal location, the presence of various shunts, or pathological connection of arteries and veins leading to direct discharge of blood from one pool to another, bypassing the capillary network. All this gives birth noise that is heard in reality.

Subjective tinnitus, which is actually absent, may be the result of metabolic disorders and intoxication. TO hepatitis, diabetes, atherosclerosis, a sharp drop in sugar in the blood, that is, hypoglycemia, impaired thyroid function. More often, the pathology of ENT organs leads to subjective noise: otitis, sulfur plug, varying degrees of otosclerosis, sensorineural hearing loss and barotrauma, inflammation of the inner ear, i.e. labyrinthitis and Meniere’s disease, another pathology.

Tumor of the cerebellar cerebellar angle is quite widespread, and especially auditory nerve neuroma, which may be the source noise. Many medications are to blame for tinnitus. These are ototoxic antibiotics, for example kanamycin. it maybe methyl alcohol, it causes not only blindness. IN in some cases, osteochondrosis of the cervical spine is to blame, which causes neurovascular symptoms, production factors, as well as multiple sclerosis. There are other reasons to understand which is the task of both an ENT doctor and otoneurologist.

Listen to the noise!

As a rule, if the maze and the snail are damaged, then the noise is very strong and painful. If there is an intracranial tumor, then noise usually associated with headache. The more headache you have, the more stronger and tinnitus, while it is able to decrease with a decrease intracranial pressure. If the patient has a swelling of the back cranial fossa, then the noise will respond to a change in body position in space, and if there is a suspicion of a tumor of the cerebellar cerebellum angle, then the noise will be asymmetric, and localized in half head, in the back of the head or from the side of one ear. Vascular noise will be pulsate, and the patient will say that he has a soft blow, or a sizzling shade. If you push the jugular vein to such a patient, then you can sometimes hear from him complaints about the strengthening of such noise.

If a person has a dysfunction of the auditory tube, or sound-conducting systems of the middle and outer ear, it is most often noise has a low frequency, hearing falls, and is felt in the affected ear congestion. A typical course of Meniere’s disease causes tinnitus. Usually, the noise amplifies before an attack of illness; reaches in the midst of an attack, and then decreases.

Finally, there are many congenital and hereditary conditions in which tinnitus is characteristic. This is a syndrome Arnold-Chiari, with violation of the structure of the arms of Atlanta and lowering cerebellar tonsils below anatomical boundaries, hereditary auditory nerve neuroma, vertebral abnormalities, hereditary defeat of the cranked ganglion.

If you blow your nose sharply, dive quickly or rise from the depths, during take-off and landing of the aircraft, tinnitus may occur as consequence of barotrauma. In extreme cases, there is pain in the ear, stunning, nausea, and dizziness. Very often lead to barotrauma explosions as well as shots at close range from ear.

In the event that there is a tumor of the middle ear, then it may be a combination of hearing loss with one-way pulsating noise. Special the doctor should carefully collect a medical history if he suspects that noise was induced by some medicine. This is currently cause many aminoglycoside antibiotics, diuretics, often occurring non-steroidal anti-inflammatory drugs – Diclofenac, Indomethacin and Ibuprofen, medicines for pressure – Enalapril, Monopril. It can be nifedipine, a medicine for depression, and other remedies. Of the antibiotics, the most ototoxic gentamicin, streptomycin, kanamycin and tobramycin.

Who to contact and what to do?

In some cases, diagnosing the cause of the noise is quite simple, and sometimes a lengthy diagnostic search is required. First of all, it is necessary for an ENT doctor, an audiologist, or otoneurologist thoroughly characterize the noise, considering all its criteria, examine its dynamics, frequency, localization. The patient must it is necessary to listen to the head with an ordinary phonendoscope. Nothing funny that the doctor listens to the head with a phonendoscope, no, because in many cases, myoclonic muscle twitches can be heard, muscle contraction of the soft palate, or vascular murmur, talking about the presence of various shunts and anastomoses.

The second important examination in addition to taking an ENT doctor is audiological examination. This is an audiogram recording, conducting impedanometry, the study of auditory evoked potentials, conducting electrocochleography. Testing is very important, as biochemical and general clinical, ultrasound examination of blood vessels head and neck transcranial dopplerography. Sometimes required MRI of the brain and cervical spine, X-ray neck with rotary samples. Suspected patient pathology of ENT organs can, according to indications, be carried out microotoscopy, endoscopic nasopharyngoscopy to carefully inspect all available organs.

Treatment

Finally we got to the treatment of tinnitus. But before proceed with the description of the drugs, it should be recalled that the true cause of noise is far from always determined by doctors. Noise can be a sign of so many diseases. And in the event that the main is successfully treated a disease such as atherosclerosis or diabetes then disappears or Tinnitus is also significantly reduced.

Tinnitus can be treated both conservatively and with using surgical interventions. What are the drugs used with tinnitus? These are various vascular agents, nootropics, muscle relaxants and vitamins, antihistamines and anesthetics, diuretics and drugs that normalize blood supply auditory analyzer. Consider the drugs that are most ENT doctors often use in their practice, allowing normalize the patient’s condition, and reduce noise, or even rid him of it.

At the beginning of the description of each drug is indicated its international nonproprietary name, or INN, and then are the names of the drugs. The first is usually named the best original a drug first developed and introduced into clinical practice, and then its commercial copies, or generics. Also the price range for both the original product and for its analogues. The cost of medicines is relevant for pharmacies all forms of ownership in the Russian Federation as of September 2019 of the year. And start the review with drugs that normalize the metabolism and blood supply in the field of the organ of hearing.

The best drugs for tinnitus

Nomination a place Name of product price
FACILITIES, NORMALIZING BLOOD CIRCULATION AND EXCHANGE 1 Vinpocetine (Cavinton, Telektol) 103 rub
2 Ginkgo biloba (Tanakan, Bilobil, Ginkoum, Memoplant) 568 rub
3 Cinnarizine (Stugeron, Vertisin) 35 rub
4 Trimetazidine (Preductal MV, Ansigil, Deprenorm, Rimecor, Trimectal) 70 rub
5 Dihydroergocriptine + Caffeine (Vazobral) 986 rub
Drugs of other groups 1 Betagistin (Betaserc, Betaver, Vasaserc, Vertran, Vestibo, Tagista) 71 rub
2 Chlorpromazine 145 RUB
3 Milgamma 332 rub

Blood circulation and metabolism normalizing agents

These drugs include vinpocetine, Ginkgo Biloba derivatives, ergot, slow calcium blockers channels, as well as antihypoxants. Of course, they apply not only with tinnitus, but also with other diseases. After all, special a medicine that is used only for tinnitus and nowhere more, science is still unknown.

Vinpocetine (Cavinton, Telektol)

Popularity Rating: 4.9

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Vinpocetine has already been repeatedly described in various medicinal reviews as a remedy for chronic cerebral ischemia, for improve memory, attention. Vinpocetine is a modified vinca alkaloid, its task is to optimize cerebral blood flow, it dilates blood vessels, and reduces aggregation, or adhesion platelets among themselves. In addition to tinnitus and hearing loss, the drug indicated for vascular dementia, ischemic strokes. Assigned Cavinton with vertebrobasilar artery syndrome, with degeneration retina, encephalopathy, and Meniere’s disease. It is shown at cerebral atherosclerosis, various forms of headache, with the consequences of traumatic brain injury and decreased memory.

Cavinton and vinpocetine are taken after meals, there is a new form – Cavinton Comfort. It is more active, contains 2 tablets normal Cavinton 5 mg, that is, the dose is 10 mg. A drug taken one to 3 times a day, and is available in tablets, which dissolve, and you do not need to swallow them. Pills have pleasant orange flavor.

Cavinton Comfort 0.01 No. 30 is in pharmacies from 240 to 420 rubles., it is a Hungarian drug, company Gideon Richter. The cheapest domestic vinpocetine can be purchased at a price of 25 rubles., It is produced by the Irbit Chemical Farm, dosage of 5 mg No. 20.

Advantages and disadvantages

Cavinton’s drawback is the fact of a slight increase oxygen needs of the heart, and therefore it is not prescribed for angina pectoris, heart failure, and rhythm disturbances hearts. If Cavinton is administered parenterally intravenously, then he should be administered very slowly.

Ginkgo biloba (Tanakan, Bilobil, Ginkoum, Memoplant)

Popularity Rating: 4.8

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All Ginkgo Biloba Medicines Improves Metabolism, and blood fluidity, or its rheological properties. Besides, funds easily stimulate, have a mild antidepressant action, and at the same time are most shown to patients with short exposure to ear noise. It is important that Tanakan is well documented in modern double blinds, placebo-controlled studies.

It is very important that the plant material in Tanakan, which used for medicines, is clearly dosed and standardized. Tanakan’s reception is shown in any form cognitive deficiency, pathology of lower limb arteries, and the presence of intermittent claudication, vascular impairment of vision and hearing loss, and Raynaud’s syndrome. Apply Tanakan when hearing impairment and tinnitus, you can take one tablet three once a day, while the course of treatment is long, at least 3 months. You can take Tanakan up to six months or even longer, but only as directed by a doctor.

Tanakan, manufactured by Bofur Ipsen, is one of the best and most refined medicines containing ginkgo leaf extract Biloba. 40 mg tablets, 90 pcs. will cost from 1200 to 1900 rub., French-made drug. Much cheaper Bilobil, 60 capsules of which in the same dosage can be buy at prices from 550 rubles., production Slovenia, Krka. A drug Ginkoum, which is produced by the domestic company Evalar in that the same dosage, in the same amount, costs Tanakan will cost you from 530 to 860 rub.

Advantages and disadvantages

Tanakan is usually very well tolerated and has no effects. overdose. However, the drug may cause in rare cases, less than 1%, headache, nausea, rash, dizziness. Experience with Tanakan has shown that the severity of side effects does not depend on the duration of treatment, but in case of their the occurrence of the drug should be discontinued. Despite the good tolerance, Tanakan in tablets (and also in syrup) contraindicated in erosive gastritis, gastric ulcer, with stroke and acute myocardial infarction, with a decrease blood coagulability. The drug is not recommended for use pregnant and lactating women. Tanakan pills have lactose, therefore, it cannot be prescribed to patients with congenital disorder lactose metabolism. Perhaps the biggest disadvantage is consider high cost, and the need to take it somewhat months, but in case of tinnitus all medications taken long enough.

Cinnarizine (Stugeron, Vertisin)

Popularity Rating: 4.7

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Stugeron is a rather old drug, it was used in The Soviet Union, and among the indications should also be called migraine, transient ischemic attacks, various forms of dizziness, recovery period after strokes, both ischemic and hemorrhagic, vascular disease, and decreased memory. Often he was prescribed as a cure for headache. This medicinal the drug belongs to calcium channel blockers, which especially able to improve vestibular blood flow, as well as peripheral blood flow in the coronary vessels of the heart. Also Cinnarizine improves the body’s resistance to hypoxia.

Cinnarizine is available in 25 mg tablets, and its effect consists in inhibiting the release of vasoactive substances. it adrenaline, dopamine, histamine, bradykinin. It improves ability red blood cells to deform, reduces blood viscosity and increases it fluidity. With tinnitus, it is necessary to take the drug 25 mg, then eat one tablet three times a day. It is also shown at air or sea sickness, that is, with kinetosis, half an hour before flight or dispatch of a ship.

The drug Stugeron, which is produced by a Hungarian company Gideon Richter, will cost at a price of 186 rubles, it is 50 tablets at 25 mg The cheapest cinnarizine of the same dosage can be purchased at a price of 35 rubles, and it will be a Bulgarian drug, companies Sopharma

Advantages and disadvantages

Despite its effectiveness, strict control is necessary because prolonged use of cinnarizine in high doses may increase depressive effect and induce drug development parkinsonism.

Stugeron also has quite pronounced side effects. actions. This is abdominal discomfort and dry mouth, weight gain body with prolonged use and sweating, headache and attacks drowsiness, jaundice and allergies. It should also be remembered that the effect of stugeron may increase the intake of antidepressants, as well as alcohol.

Trimetazidine (Preductal MV, Ansigil, Deprenorm, Rimecor, Trimectal)

Popularity Rating: 4.6

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These are antihypoxic drugs that increase resistance. tissues of the middle and inner ear, the maze to a low amount oxygen, and helps increase brain and labyrinth blood flow. The most effective product and its analogues in noise in the ears will be if the patient has peripheral a disorder, for example, cochleovestibular syndrome, and in combination with cardiac pathology. In this case, the product will be increase both myocardial reserves and its resistance to hypoxia. It is necessary to apply Preductal one tablet twice a day, while eating.

The best quality is considered the original drug Preductal sustained release (MV) manufactured by Servier (France), but it is not always in pharmacies. One pack of capsules 35 mg No. 60 can be purchased in pharmacies at a price of 2964 rubles. The cheapest trimetazidine is probably 20 mg No. 30 tablets, which will cost from 70 rubles. and higher. This is domestic trimetazidine manufactured by Ozon. What substance is there, and why it is so cheap is unknown.

Advantages and disadvantages

When taking Preductal, contraindications must be considered. it extrapyramidal system disorders, Parkinson’s disease and syndrome restless legs, severe renal failure, pregnancy, the period of breastfeeding and face up to 18 years of age. May there are side effects, among which the most common pain abdominal diarrhea, dizziness, and gait instability, skin rash.

Dihydroergocriptine + Caffeine (Vazobral)

Popularity Rating: 4.5

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This medicine is a derivative of ergot alkaloids, in which added caffeine to balance effects. As a result of this the medicine blocks alpha adrenergic receptors that are located in vessels, and simultaneously stimulates the structure of the central nervous systems that regulate the synthesis of serotonin and dopamine. At the effect of the drug decreases vascular permeability, falls aggregation of blood cells, increased blood flow, and metabolism in the structures of the brain is intensified. All this leads to increased tissue resistance, and their ability tolerate hypoxia. Caffeine additionally stimulates the bark brain, improves vasomotor and respiratory center, and helps to increase mental performance, reduces fatigue.

In addition to tinnitus and tinnitus, vazobral is indicated for cerebral atherosclerosis, in complex therapy during rehabilitation measures after a stroke, with Meniere’s disease, and with treatment acute and chronic labyrinthitis. Apply vazobral inside 1 tablet 2 times a day, the duration of treatment is at least 2 months, And if necessary, then the courses can be repeated up to 2 times a year. Vazobral is not cheap, a pack of 30 tablets will cost from 986 rubles.

Advantages and disadvantages

The disadvantage of Vazobral can be considered its high cost, and also some side effects that occur most often nausea, abdominal discomfort, and dyspepsia symptoms, i.e. a feeling of heaviness in the abdomen, bloating, belching, and so on. At the occurrence of such symptoms from the gastrointestinal of the tract, as stated in the official instructions, drug withdrawal is not required. Very rarely there is tachycardia, a decrease in arterial pressure, as well as interactions with certain medications for pressure when they will enhance their effect.

Drugs of other groups

Because medications used to treat noise in the ears from other groups, applied piece by piece, then we solved them all combine together. This will include medicines that modulate histaminergic transmission, various derivatives phenothiazine, which are antipsychotics, and block pathological vegetative afferentation. These are tranquilizers, which are also prescribed in the complex treatment of ear noise and with sleep disturbance, phenobarbital, which have pronounced sedative effect, and is used as drugs of the 2nd stage. This also includes psychostimulants, which are used with anticholinergics, and antihistamines, which potentiates their effect. Also, these are B vitamins, and other drugs, consider some of them in more detail.

Betagistin (Betaserc, Betaver, Vasaserc, Vertran, Vestibo, Tagista)

Popularity Rating: 4.9

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Betahistin is a histamine receptor blocker, modulates the transmission of histamine and serotonin, not only effective with tinnitus, but also with other vestibular disorders: this dizziness, nausea, and vomiting.

Betaserk causes the expansion of the arterial part of the capillaries, normalizes the pressure gradient of the endolymph in the labyrinth and in the tissues snails, which improves the condition in patients with dizziness. Along the way, it increases the tone of the smooth muscles of the bronchial tree and the gastrointestinal tract, which leads to increased secretion gastric juice. Betagistin is indicated for vestibular neuronitis, with benign positional dizziness, as a means prevention after neurosurgical operations, with vertebrobasilar insufficiency.

Take the drug at the beginning of therapy, preferably 8 mg or 16 mg 3 times a day. Treatment should be long, but duration determined by the doctor.

The drug has a different dosage, tablets of 16 mg per the amount of 30 pieces will cost 608 rubles. 24 mg tablets 20 pieces from 529 rubles, and 24 mg tablets of 60 pieces will cost from 1283 rubles. Betaserk is manufactured by Abbot, The Netherlands.

The cheapest domestic Betagistin can be found in a pharmacy from 71 rubles., This is 16 mg No. 30.

Advantages and disadvantages

The product is fairly well tolerated, but has a small a range of side effects. It is undesirable to appoint when bronchial asthma, exacerbation of a stomach ulcer, as well as in the presence of pheochromocytomas. Naturally, the drug is contraindicated in pregnant women, especially in the first trimester, as well as during breastfeeding. If the patient causes dyspeptic symptoms on the medicine, then Betagistin is then best taken after meals. If the patient has allergy, and he takes antihistamines, then they lower the effect of taking Betaserc, this must be remembered.

Chlorpromazine

Popularity Rating: 4.8

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Aminazine blocks vegetative impulses in the parasympathetic nuclei and in the cortical parts of the auditory analyzer. He is blocking central contacts between adrenergic and dopaminergic synapses. The drug is rarely prescribed in combination therapy and only in severe cases. Aminazine refers to antipsychotics, and this means that he is a strictly prescription drug. They are usually treated psychoses, phobias, withdrawal symptoms and delirium tremens then eat delirium tremens. It is also used to treat delusions and hallucinations, so the main spectrum of use is psychiatry, big and small. However, it is also used in the treatment of dermatitis, with vomiting in pregnant women, with Meniere’s disease and others hearing impairment and vestibular function, including noise in the ears.

The drug is available in tablets and ampoules, for the treatment of noise in in the ears it is used only in complex therapy, in severe cases and in small doses, which is determined by the doctor.

A pack of 10 tablets of chlorpromazine 50 mg can be bought at a price from 200 rubles, it is produced by a Russian pharmaceutical company Valenta Pharmaceuticals.

Advantages and disadvantages

Aminazine cannot be used for a long time, this drug exclusively prescription, and even ENT doctors can have difficulties with prescribing it. It is contraindicated in all severe disorders of the function of internal organs, including with cardiovascular disease, with prostatic hyperplasia glands. Aminazine has pronounced side effects, including extrapyramidal and parkinsonian reactions, falling blood pressure, jaundice and leukopenia may occur. On the against the background of reception, impotence may develop, menstrual irregularity cycle and increase body weight.

There are a lot of special instructions, for example, a ban on admission alcohol in the treatment with chlorpromazine, and there are also many drug interactions. So, chlorpromazine lowers the threshold convulsive readiness, if used together with anticonvulsants if prescribed together with medications for increased thyroid function, it’s harmful affects blood. But in some cases, he can still stop pronounced symptoms of noise, and it is recommended for use official instructions, so he is on the list.

Milgamma

Popularity Rating: 4.7

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Finally, since the pathogenesis of tinnitus is of great importance impaired nerve conduction, reduced trophic afferent servings of the auditory nerve, nerve transmission disorder pulse and the appearance of noise, then in complex therapy is shown the use of B vitamins, which are neurotropic. One of these drugs will be the well-known Milgamma. Compositum, which is available both in tablets and in dragees. Milgamma compositum contains vitamins B1, B6, and ampoule Milgamma – and B12. In addition to tinnitus, Milgamma is prescribed for neurological diseases: trigeminal neuralgia, herpes zoster lichen, polyneuropathy, including diabetic and alcoholic, shooting pains in the back, that is, lumbago with sciatica.

The drug must be used one tablet per day, for according to the doctor’s test, the dose can be increased to one tablet three once a day. Treatment is usually a period of 1 month. Jelly beans Milgamma compositum in the amount of 30 pieces, calculated per month treatment, will cost from 625 rubles, and it produces a German company Vorvag Pharm.

Advantages and disadvantages

Milgamma also has drawbacks, these are symptoms of an overdose, which can even lead to a neurotoxic effect, and if take the medicine for longer than six months, you may experience impaired sensation and weakness in the arms and legs, i.e. the opposite effect. Despite the seeming harmlessness of vitamins, there may be side effects. This is skin itching, hives and rashes, Quincke’s edema. Sometimes there may be nausea, excessive sweating, and tachycardia, so it’s better to apply Milgamma doctor’s recommendations and under his supervision.

Perhaps more drugs that can cure from this disorder does not exist, and these individually are unlikely whether they can do something in advanced cases. Tinnitus treated comprehensively, using physiotherapeutic methods treatment, with hearing aids, especially if tinnitus combined with hearing loss. In some cases, even surgery. One of the methods affects the cervical sympathetic nodes, and the second way is to influence specific auditory structures. This is tympanoplasty, stapedoplasty. Such operations can be used to reduce tinnitus, a source which is directly the organ of hearing.

Popularity rating based on analysis of demand data service wordstat.yandex.ru.


Attention! This rating is subjective, not advertising and does not serve as a guide to the purchase. Before the purchase consultation with a specialist is necessary.

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