8 best remedies for herpes

Review of the best according to the editors. About the selection criteria. The the material is subjective, is not advertising and is not serves as a guide to the purchase. Before purchase is needed consultation with a specialist.

All people, sooner or later, face one of the manifestations herpes infection, which is manifested by the usual “cold lips “, or signs of labial herpes. But herpetic infection is a much more serious and complex problem. There are several families of herpes viruses, and a person can affected not only the skin, but also the mucous membranes of the oral cavity and genitals, ophthalmic herpes or lesions may occur an eye that, without treatment, leads to blindness.

Herpetic encephalitis is extremely severe and meningoencephalitis, i.e. viral inflammation of the brain and its shells. In immunodeficient patients, herpetic lesions of internal organs such as hepatitis or pneumonia. The intrauterine herpetic infection is very difficult, which often leads to severe damage to the skin and central nervous system in infants. If left untreated, more than 60% newborns dies.

Herpetic infection in HIV-infected individuals that is rapidly becoming generalized. There are long-term effects of herpetic infection. So, with shingles, or intercostal neuralgia, caused by herpes, after many years may continue persistent and burning neuropathic pain along the intercostal nerves, they are very difficult to treat, lead to insomnia, neurosis, and in in some cases even cause suicide.

Almost no people who do not exist in the body herpes viruses. We all become infected with viruses in early childhood, and more than 90% of all healthy people have specific antibodies to these viruses. So, the herpes simplex virus is already detected with 18 months of age in almost all babies, and with the beginning antibodies to genital herpes virus appear. Only in healthy people herpes viruses “doze” in latent form in the cells of the central nervous system, and immunity does not allow them be activated. And in people with immunodeficiency, they begin multiply, and symptoms of acute or chronic appear infection.

That’s why you need to be able to navigate the means that can quickly inactivate herpes, and in this rating will be reviewed drugs with antiviral efficacy, and also able to enhance the immunity of patients, and activate internal mechanisms of the body’s struggle. In conclusion, there will be ointments and creams for the treatment of herpetic eruptions on skin and mucous membranes.

Rating of the best remedies for herpes

Nomination a place Name of product price
The best antiviral drugs for herpes 1 Acyclovir (Zovirax) 250 rub
2 Valaciclovir (Valtrex, Vairova, Valvir, Valtsikon, Vacyrex) 1 264 rub.
3 Famciclovir (Famvir, Minaker, Familar) 1 535 rub.
Herpes Immune Remedies: Truth and Fiction
The best herpes remedies for local treatment 1 Erazaban 423 rub
2 Virgan
3 Oftaquix 237 r
4 Fenistil Pencivir 355 rub
5 Oxolinic ointment 53 rub

The best antiviral drugs for herpes

The first antiviral drug that is still very widely used in practice, was created in the early eighties years. This is acyclovir. But despite over forty the history of the use of this tool, it is still the most commonly prescribed cold sore medicine. Already more than 50 million. patients worldwide evaluated his ability to eliminate herpetic rash.

In addition to acyclovir, such agents have been introduced into clinical practice, like Famvir (famciclovir) and Valtrex (valaciclovir). Activity antiviral remedies for herpes are gradually increasing from acyclovir to famciclovir. Valacyclovir is intermediate position.

An antiviral medicine for herpes can be prescribed by two different ways:

  1. single, or episodic appointment with the onset of symptoms herpes in a healthy person;
  2. prolonged therapy.

If in the first case the medicine is prescribed in short courses, lasting about a week, then in the second case the patient It is treated daily, and the course of treatment is months, and even years. In the second case, the task is to prevent relapse chronic infection in patients with severe immunodeficiency, with HIV infection, and in other clinical complex cases.

Acyclovir (Zovirax)

Rating: 4.9

Zovirax

Zovirax is the original drug of acyclovir, and manufactured by the pharmaceutical company Glaxo Smith Kline, Great Britain. Zovirax is available in tablets of 200 and 400 mg acyclovir in each, as well as in the form of an eye ointment, cream for topical and in powder form for intravenous injection in severe forms of herpes.

The mechanism of action of the drug is the deception of the virus, and the use of defective building material for its DNA. IN the result is a break in the DNA helix, which stops reproduction the virus. This mechanism is reliable and proven.

Zovirax is prescribed for adults with herpes simplex, or herpes on the lips, for the prevention of herpes infection, for treatment chicken pox and shingles. There are also others indications for individual groups of patients. Zovirax tablets must be used with food, washed down with water.

Take Zovirax often, every 4 hours, which makes 5 receptions a day. The average course of treatment does not continue less than 5 days, but can be extended according to indications and on the recommendation specialists. For the prevention of recurrence of herpetic infection it is necessary to take the drug every 6 hours, that is 4 times per day, or according to another scheme recommended by a doctor. For treatment chickenpox and immunocompromised patients have their own dosage. The cost of 25 tablets of Zovirax is about 460 rub.

Advantages and disadvantages

Zovirax, and other drugs containing acyclovir, there are perhaps only two drawbacks. The first is too rapid metabolism and breakdown of this drug in the body of a person, therefore, you can’t avoid the frequent use of the drug. The second drawback is that over the 40 years since days of the introduction of acyclovir into clinical practice, more powerful drugs, although acyclovir continues to be the main one, reliable and popular tool. Very important positive the moment is the possibility of using the drug in pregnant women women and with lactation, this is important in the prevention of herpetic infections in newborns.

Acyclovir has side effects such as nausea, rash, increased activity of liver enzymes. It’s important that the use of acyclovir can be carried out with treatment HIV infection, it does not cause any drug effects interactions.

Valaciclovir (Valtrex, Vairova, Valvir, Valtsikon, Vacyrex)

Rating: 4.8

Valtrex

Valacyclovir, the next generation antiviral drug, It is also represented by a large variety in drugstore counters. The original drug that first entered the market is Valtrex drug, it is produced by the English company Glaxo Smith Klein, formerly known as Glaxo Wellcome.

Valacyclovir is a much more active remedy for herpes treatment than Acyclovir, but the curious fact is that once in the body, valaciclovir is influenced by a liver enzyme turns into acyclovir – the older antiviral drug generation “? described above. But at the same time a package of 10 tablets Valtrex 500 mg for some reason costs from 960 rubles. and higher. In what cause?

The thing is that Valtrex has such features pharmacokinetics and pharmacodynamics that they allow acyclovir, as an active metabolite, stay in the body at a higher concentration. As a result, you can take Valtrex much more convenient way – just one tablet in the morning and one tablet in the evening, and not at all 5 times, like Zovirax. Plain the total daily dose is 1 or 2 g. In addition, the resulting constant concentration of acyclovir as an active metabolite allows the drug to act on the herpes virus in more complex cases.

If Zovirax is well suited for treating a common cold lips, then Valtrex is used to treat shingles, with genital herpes, in immunodeficiency states, in order to prevention of cytomegalovirus infection, as well as for treatment Herpes zoster, affecting the eye area when affected facial and trigeminal nerves (dangerous localization with possible the development of ophthalmic herpes). In the event that patients there is a recurrent type of herpetic lesion, then it is necessary to immediately begin treatment with this drug, within 3 or 5 days, But as prescribed by the doctor, the period can be increased to 10 days, and the dose is also increased.

Valtrex is a fairly expensive treatment herpes. So, 10 tablets of 0.5 g, designed for 5 days of admission with the usual, non-relapsing form of herpes can be purchased for 960 rub.

Advantages and disadvantages

In a first approximation, Valtrex can be considered a form of acyclovir, which acts in the body powerfully and constantly, and is deprived of it disadvantages. But Valtrex has its own characteristics. It is impossible it is used in children and adolescents, it is intended for adults, over 18 years old. Use it with caution if available renal failure, and data on the use of Valtrex in not enough pregnant and nursing mothers. And although there is no explicit ban on the use of the drug, but apply it can only be if the benefits of the reception are superior possible risk to the fetus.

Side effects often led to headaches and nausea, less commonly, allergic rashes and itching. Valacyclovir may be considered a drug that can cope with herpetic damage to the eyes, and also prevent the transmission of genital herpes to healthy to a sexual partner, which is not always possible for a simple acyclovir.

Famciclovir (Famvir, Minaker, Familar)

Rating: 4.7

Famvir

Famvir is the newest and most advanced antiviral herpes medicine, which after ingestion turns into The active metabolite is pencivir. Pencivir is not only active in against herpes viruses, but also capable of inhibiting the reproduction of the virus chickenpox, Epstein-Barr virus and CMV (cytomegalovirus infection). The tool acts on the hereditary material of viruses, suppressing the doubling of DNA strands and inhibiting the reproduction of viral particles – replication. Thus, famciclovir, as described above Valaciclovir is not an active drug, but a prodrug, which are activated in the human body under the influence of hepatic enzymes.

Famvir is indicated for the treatment of various forms of herpes and shingles caused by chickenpox virus. His prescribed for the prevention and treatment of exacerbations in relapsing herpetic infection, including in patients with reduced immunity. Famciclovir is more likely to eliminate shingles, and treatment of herpes with this remedy contributes to the least amount of residual phenomena in the form postherpetic neuralgia.

It is recommended to use Famvir, on average, 500 mg 3 times a day for 7 days. This dosage is recommended for herpetic damage to the eyes, with shingles, as well as with some other forms of herpes infection. Exist various dosage regimens indicated by the attending physician.

Manufactured by Famvir pharmaceutical company Novartis, and at a price this herpes cure is an absolute leader in Russian the market. Three 500 mg tablets are available at a price. from 1350 rub. Thus, the comma exchange rate of this remedy, for example, for the treatment of ophthalmic herpes will be about 9500 rub. during the week. Of course, taken by itself, this price seems large, but if it avoids blindness, then it can be generally do not take into account.

Advantages and disadvantages

The advantages of famciclovir include its highest bioavailability of all these drugs, and therefore and activity. This remedy is well tolerated, and low immunity in patients with HIV infection is not an obstacle to his application. Of the side effects, they were most often mild severe headache and nausea. Overdose data practically unknown. In general, we can say that the original Novartis Famciclovir Gold standard “for the treatment of severe herpes infections. The only negative is the rather high price, as well as the output form for internal use only, in tablet form. Not doubts that in the future famciclovir will be available in forms for parenteral, intravenous administration, why it efficacy in severe forms of herpes infection significantly will increase.

Herpes Immune Remedies: Truth and Fiction

In various domestic recommendations for the treatment of herpes infections can often be seen in patients drugs that are inducers of interferons, or agents that stimulate the production of this substance with antiviral activity in the human body.

Patients are indicated for taking drugs such as Amixin, Ridostin, Cycloferon, and even Kagocel. Often domestic experts advise using interferons proper, such as Viferon, Reaferon and other medicines in order to raise own non-specific immunity with antiviral activity. Are these drugs really good at fighting herpes virus, as well as antiviral agents, with a well-known mechanism of action, which was described above? Let’s try sort out this situation.

We give data on the first named drug – Amiksin. If a go to pharmacies and see which companies produce Amiksin and similar drugs, the active substance of which is tiloron, then you can see what it is: a domestic company Pharmstandard, producing Amiksin, Nizhpharm company, producing Lavomax, Dalchimpharm, which produces an analog of Tilaxin, a company Ozone, with an analogue of Tiloram, and so on.

It is immediately evident that among the manufacturers there are no leading world leaders in the pharmaceutical industry who produce drugs of the first group, with proven antiviral activity. What is the matter?

Amiksin is used very widely in Russia for many viral infections, for the prevention of influenza, with hepatitis, with acute respiratory viral infections and with herpes. In the instructions to him you can read what is for him only adverse reactions such as allergies, dyspepsia and chills. The instructions say that it is contraindicated in taking pregnant, but why is not clear.

Despite the fact that this drug is really in the laboratory, that is, in vitro, showed a fairly high synthesis activity interferon, it is not used abroad. This drug had serious side effects have been identified – such as adverse effects on fetal development, or embryotoxicity. Clinical studies were stopped due to side effects. International evidence-based studies conducted with high Amiksin no confidence level, World Organization Health (WHO) has no information about him, in developed countries of Europe and the USA it is not used. Links confirming given information:

  1. http://journals.sagepub.com/doi/abs/10.3109/10915819409140990 embryotoxicity;
  2. https://www.ncbi.nlm.nih.gov/pubmed/1720315 ability Amiksin induce mucopolysaccharidosis.

As for other interferon inducers, such a drug, both cycloferon and ridostin are also not registered outside CIS countries, and in North America and Western Europe, this a medicine like cycloferon is unknown. There are many works on cycloferon but not a single randomized clinical a high level of evidence study (RCT) there is no drug for this drug, and its clinical effectiveness is not proven.

But maybe if the interferon inducers do not have a proven effectiveness, interferon may be introduced into the body can help protect against cold sores? Maybe Viferon, which is produced in different dosage forms, really helps? Viferon, for example, is available as an ointment, in the form of rectal suppositories of four dosages, in the form of a gel for local application.

Alas, in experiments it was proved long ago that direct and continuous exposure to exogenous or externally administered interferon per cell should last at least 4 hours, moreover in high doses. Therefore, instillation of interferon in the nose, the introduction it in candles and smearing it on the surface of the skin cannot give no real benefits to help overcome herpetic infection.

It’s quite another thing when used for topical use ointments, creams and gels that contain truly effective antiviral drugs: the same acyclovir, penciclovir, ganciclovir, and other antiviral agents. So it came time to move from funds with dubious effectiveness that are not apply in developed countries to local herpetic treatment infection.

The best herpes remedies for local treatment

The best way to achieve an early elimination of herpetic rashes on the skin and on the mucous membranes – this is a combination effective intake of antiviral drugs by mouth, with the creation of the current concentration of the medicine for herpes in the blood, and applying on the skin and on the mucous membranes that stop replication virus in the skin and the appearance of new foci of vesicle rash. All antiviral ointments and creams must be used in the same way as pills – immediately at the initial diagnosis, or even more earlier, at the stage of prodromal phenomena, when the bubble rash is still not.

In this case, the patient in the classical case may experience Amid common cold symptoms, mild irritation on skin in the region of the nasolabial triangle, and along these unpleasant sensations a person who already has sufficient experience understands that on the next day he will have herpetic eruptions. In such case, you must immediately start using special local drugs that will help inactivate the manifestation infections outside.

It should be remembered that you can not touch herpetic hands vesicles, as well as vesicles formed during the disease chickenpox. The fact is that if with these hands then by chance to take the eyes, then you can bring herpetic infection there, with severe damage to the cornea, then – all environments of the eye, and with Adverse immune status Ophthalmic herpes can transform into herpes encephalitis, with a high level lethality. Consider the most famous effective local remedies for the treatment of herpes infection.

Erazaban

Rating: 4.9

Erazaban

The active substance of Erazaban cream is docosanol. is he has a unique mechanism of antiviral activity. He is not affects how drugs of the first group on a fatal change hereditary material of the herpes virus, and acts on the mechanism the penetration of the virus into the cell. One of the key points of this the mechanism is the initial fusion of the virus with the cellular the membrane. It is at this stage of pathogenesis that provenol is affected.

Erasaban is applied to the area of ​​vesicle viral rashes on skin, as well as to neighboring healthy areas, and is used by adults patients, and in children over 12 years of age, for 4-6 days. In if the patient applied this cream before the rash appears, with prodromal symptoms, then the use of Erasaban in general prevents the development of bubble rashes. On average, after 1 or 2 days after the start of treatment, a significant improvement occurs or even the complete elimination of the rash, but still, in order to effect was the best, you need to apply the cream for 5 days, and even longer. Erasaban is produced by Health Care brands International, and you can buy a cream packaged in small tubes of 2 g, for 400 rub

Advantages and disadvantages

The only drawback of Erasaban is the rather frequent the need to apply it to the skin. Every 3 hours you must update the applied cream, and you need to do this five times in day. A side effect is dry skin, and slight itching, tingling, or burning on those areas of the skin where the cream is applied. But most patients tolerates it well, but it is not recommended to apply it on the skin near the eyes. The only limitations are patients with severe immunodeficiency and pregnant, but not due to the development of special adverse events effects, and due to the lack of full-scale clinical research. In patients with liver and kidney disease, the cream may apply as normal.

Virgan

Rating: 4.8

Virgan

Virgan is a special gel that is designed exclusively for use in ocular forms of herpes. Virgan contain ganciclovir, which is close in its mechanism of action to acyclovir, and using competitive inhibition disrupts the formation of viral hereditary material. This gel is active not only for herpes and chickenpox viruses, but also in against the causative agent of cytomegalovirus infection and the virus Epstein-Barr.

This cream is used as part of complex therapy in the treatment of herpetic superficial keratitis, for treatment cytomegalovirus infection and for the prevention of ocular formation AIDS complications. This gel is recommended for the prevention of transplant immunodeficiencies when the patient receives massive doses of immunosuppressive drugs, or chemotherapy in connection with the upcoming or occurred organ transplantation.

The gel has an opalescent appearance, and has a low viscosity, therefore, it is not smeared, but buried in the eyes, in the area lower conjunctiva, from 3 to 5 times a day. Average the duration of the course of treatment is 2 weeks, but not less than 7 and not more than 21 days. Since the conjunctiva has an increased ability to absorb, then virgan may cause slight pain, blurred vision, symptoms of eye irritation and development conjunctival hyperemia. Manufactured by Virgan Laboratoires THÉA, (France), and its average cost is about 900 rubles.

Advantages and disadvantages

The advantages of Virgan include high antiviral activity, good absorption and its distribution in the intraocular environments, relatively low resorption capacity in systemic blood flow. Ganciclovir is an antiviral agent the next generation, and more active than usual eye ointment, containing acyclovir. The disadvantages include a ban on it use in children under 12 years of age, the need to store it in cool place. Patients with contact lenses need to remember that if an ophthalmologist suspected a risk of developing ophthalmic herpes, then lenses must be unambiguously removed and not worn until this risk will disappear, or until the manifestations of the infection are completely cured.

Oftaquix

Rating: 4.7

Oftaquix

Surprisingly, those also used to treat ophthalmic herpes drugs that have no proven effect on herpesvirus have. For example, we are talking about a drug like Oftaquix, which comes in the form of eye drops and contains levofloxacin. This substance is classified as fluoroquinolones, and is able to suppress the reproduction of large quantities pathogens, various bacteria, but still related to cellular life forms, unlike viruses.

But such means should be used for prevention accession of a secondary infection, especially if ophthalmic herpes has already reached the stage of ulceration, and the patient there is a high risk of developing a complication such as acute purulent keratitis, iridocyclitis, or creeping corneal ulcer. No one the most effective antiviral drug does not affect reproduction ordinary pyogenic staphylococci, and the doctor must take this fact into account. In the event that the patient lives enough far, and he can get to the doctor in just a few days, but there is a pharmacy nearby, then he needs to not only dig in eyes antiviral agents, but also reinforce their action the use of local antimicrobials. For the treatment of skin rashes, as a rule, such “reinsurance” is not required.

Oftakviks to drip for prevention is necessary every 2 hours, one or two drops into the affected eye. From day 3 treatment, the drug is instilled twice less, and the course is usually no more than 5 days. It’s not necessary to dig into the conjunctiva, but directly to the cornea, that is, to the “eye itself.”

Oftaquix is ​​produced by the Finnish company Santen, and one bottle, containing 5 ml drops, can be purchased for 185 rubles.

Advantages and disadvantages

The advantages of Oftaquix is ​​a reliable cover, under with which treatment of ocular herpes can be safer. It is active against many gram-negative and gram-positive microorganisms, well preserved in the lacrimal film, and is widely used for prevention. From side effects, you can highlight a slight burning sensation in the eye, which can occur in 10% of cases and, most often, passes by yourself. Oftakviks is contraindicated in pregnant women and lactating women, as well as with increased sensitivity. In the nursery he may be prescribed by age, but with caution.

Fenistil Pencivir

Rating: 4.7

Fenistil Pencivir

This cream, produced by a well-known pharmaceutical concern Novartis, contains an antiviral drug – pencivir. It is also an active metabolite, and acts on hereditary herpes virus material. For comparison, when laboratory studies have shown that pencivir is capable of be inside the cells and cope with the virus several times longer than acyclovir. But despite laboratory tests, applying the cream must be repeated every 2-3 hours, for except for a night break. But with such an uncomfortable mode, for 3-4 the day, the cream produces the necessary therapeutic effect, and disappears the need to use it for a week or even longer. The cost of a tube weighing 2 g starts at 280 rubles.

Advantages and disadvantages

As with any drug, individual intolerance to the components of the cream is a contraindication to it use. There have been no large-scale clinical studies on use of the cream in children under 12 years of age, therefore it is also contraindicated for early childhood. But in the period pregnancy and lactation, this product is applied to the skin possible, but very carefully, after consultation with the attending physician, and only if the benefits of this drug exceed possible risk. As for the advantages of this tool, it can help when acyclovir is for topical use works slowly, or a short course is needed.

Oxolinic ointment

Rating: 4.6

Oxolinic ointment

With oxolinic ointment, which is recommended by some domestic guidelines, as an antiviral local remedy, the situation is exactly the same as with interferons and its inductors. It is produced, including in the form of an intranasal form, only domestic enterprises, and proven effectiveness, both antiherpetic and antiviral in general, it does not have. Chemists know oxolinic acid, which, in fact, has at least in vitro antimicrobial activity, but no information about scientific research abroad, and even more so about the registration of drugs, and the introduction of extensive clinical practice of agents containing oxolin, or (dioxotetrahydroxytetrahydronaphthalene) we will not find. In countries North America and Western Europe, this tool is not used, and World Health Organization (WHO) has no recommendations for its use for the treatment and prevention of herpes. Therefore, the decision to use oxolin in Russia is only a “tribute” traditions”.

Conclusion

Unfortunately, many tend to underestimate the danger herpetic eruptions, and often do not treat them at all, especially if the patient is accustomed to the fact that he has a cold and rainy season every year there are signs of labial herpes, or “colds” on lips. This impression is misleading. For example, such a sharp a disease like Bell palsy, or facial paresis, with which paralyzes one half of the facial muscles of the muscle persons most often occurs due to herpetic infection. The facial nerve swells in its narrowest place, where it passes in channel of the temporal bone. It is from the speed of appointment antiviral therapy in the first hours of onset of signs paralysis depends on the rate of regression of neurological symptoms. In such cases, treatment should immediately begin with drugs with antiviral activity inside, and maintain them applying ointment and cream to the skin of the face.

In the case of the appearance of vesicular rashes along the intercostal nerves, the same rigorous and rigorous approach to combined prescription of drugs. Result untreated intercostal neuralgia can be painful, persistent, perennial neuropathic pains that are extremely difficult to treat.

Therefore medical literacy of the general population, and timely initiation of antiviral therapy may serve pledge if inferior recovery, then significant inactivation of the virus and its reverse transition into dormant and inactive state.

And if, instead of immediately contacting a doctor, and starting urgently use antiviral drugs with proven efficiency, the patient will rely on homeopathic remedies, on compresses and traditional medicine, then most likely he will remain with partial paralysis of the facial muscles throughout remaining life.


Attention! This rating is subjective, not advertising and does not serve as a guide to the purchase. Before the purchase consultation with a specialist is necessary.

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