6 modern antihistamines for children from a year

Review of the best according to the editors. About the selection criteria. The the material is subjective, is not advertising and is not serves as a guide to the purchase. Before purchase is needed consultation with a specialist.

To medicines that are prescribed to young children, Doctors, and especially parents, should always have a special Attention. Kids cannot complain about the occurrence of side effects. effects, and if parents do not see them with their own eyes, then it is possible the wrong appointment, or in general, “self-medication” significantly worsen the condition of the baby.

During the first year of life, a little person learns a new the world, and, among other things, meets with a huge number of different allergens. This is complementary foods that are introduced after a few months. life, these are various household allergens, such as house dust, detergents, fabrics, and in summer – even insect bites. therefore many parents are rightly worried by the question: what anti-allergic and antihistamines can be safely give to young children?

There are relatively few such drugs. Besides, that in general, less drugs are used in pediatrics than for adults, there are basic physical limitations on the use of a particular drug, and even commercial. Explain these varieties of restrictions.

About the different limitations in pediatrics

Physical limitations include impossibility of taking certain medicines in the form of tablets for babies because they simply cannot swallow them, and can choke. IN In this case, manufacturers sometimes produce special children’s dosage forms, usually in liquid form, in the form of drops or in the form of syrup. So, in drops is a popular drug Fenistil, which also still exists in local form in the form of a gel. In the form of drops for babies, one of the drugs cetirizine is released, for example Zodak, which is also actively used by children allergists, immunologists and pediatricians in their clinical practice.

Sometimes a situation arises that one dosage form the same medicine is indicated for use in infants, and the other is not. An example is an old, well-known drug Diphenhydramine, or diphenhydramine, which can be used in ampoules for intramuscular and intravenous administration in children of the first year life, and in tablets, his initial intake is allowed later, and not just because they are hard to swallow.

It would seem that you can find a simple way out: crush tablet, dilute it in water and give the baby a drink. However, here everything not so easy. Since the manufacturer announced in advance that tablets are not intended for babies, therefore, the dosage in tablets may be suitable only for adults, and for children to be too big. Therefore, the tablet will have to be divided into several parts, which can cause an error and overdose. For the same We read Diphenhydramine: “When administered orally, single doses for children in up to 1 year old – 2-5 mg; from 2 to 5 years – 5-15 mg. “All this good, but one small, and fragile diphenhydramine tablet contains 0.05 g, i.e. 50 mg. It turns out that a one-year-old baby has to contrive separate no more than 1/10 tablets, otherwise an overdose is possible. FROM on the other hand, the taste of Diphenhydramine is unpleasant, bitterly burning, and the child will simply refuse to drink what his parents did.

Therefore, such irresponsible experiments should be abandoned, which can negatively affect the health of the child, and strictly Follow the instructions, using special, children’s dosages.

What does a commercial restriction mean? It is quite frequent a situation where the drug sells very well in adults, and its market promotion strategy simply does not imply expansion towards this niche. The company is not going to conduct additional expensive clinical action studies medicines for children and pregnant women. Why spend money when and so the product sells well? In this case, the instructions usually it is indicated that “the medicine is contraindicated in children (for example, before 12 years old), pregnant and lactating women. Sometimes further attributed that “no relevant studies have been conducted”, or “small amount of data has been accumulated” Again, and in this case it’s necessary strictly follow the official instructions, and do not take risks.

About indications for use

When are antihistamines most commonly used in children? In the case of well-known allergic symptoms, such as like urticaria, pruritic dermatoses, profuse, watery rhinorrhea, nasal congestion by type of allergic rhinitis, conjunctivitis, the phenomenon of bronchospasm, with wheezing and night cough. However the rule remains that antihistamines should appoint either a local pediatrician or a pediatric allergist, since many diseases can hide under the guise of a common allergy, and they need to be treated with other methods and drugs.

It should be remembered that without exception all antihistamines medicines are a pathogenetic therapy, i.e. a method of treatment that breaks a certain pathological process, and as a result reduces the severity of one or another symptom, or completely eliminates it. But the fact that the baby it became more comfortable to exist, since itchy skin disappeared, not at all says that he recovered. For example, the impact of such allergen, like dried fish food, including small copepods – daphnia – is very harmful to health, is a strong allergen, and may result in development bronchial asthma.

But if you constantly, for a long time give the child modern antihistamines, and simply (and successfully!) fight complaints, then he may not have symptoms such as barking cough, bronchospasm, skin itching, urticaria. It can put to sleep parental vigilance but anyway since elimination allergen is not produced, then the risk of developing subsequently is very high bronchial asthma. That is why antihistamines are prescribed Only a doctor should use the drugs, and they should be used exclusively short courses, with rare exceptions, for example, if available diagnosis of atopic dermatitis, and other serious disorders.

If, however, we are talking about a rather long-term use antihistamines, from 1 week or longer, then of course the benefits you need to give preference to the drugs of the second generations. Firstly, it is the convenience of a single dose, and secondly – lack of sedation. However, all medicinal 2nd generation drugs can potentially cause side effects, affect the cardiovascular system, and therefore in any case The course should be as short as possible.

But if we are talking about an acute allergic attack, for example, of the same urticaria, Quincke’s edema, then the babies from a year and older, you must take first-generation drugs. What if an ambulance doctor arrives, then they can be entered intramuscularly. This is the same Diphenhydramine, and Suprastin, they are good stop the manifestation of any allergic reaction, except for the severe, namely anaphylactic shock, when already required corticosteroid hormones, and this therapy is enough.

Before listing a relatively small assortment antihistamines for children over one year old, it should be said that this drug review will not drugs from the group of corticosteroid hormones. That is here only histamine receptor blockers which are safer.

Drug therapy

Before starting the drug review, recall that first The international non-proprietary name is given, i.e. INN. Then – the first drug in brackets is usually the most expensive, original, which was first introduced to the market, and to which all other commercial copies are equal in quality, or generics. They are also listed in parentheses after the first original drug. The following is the range of pharmacy prices, in this case we are talking about the original drug, which is the most expensive. We won’t save on children.

This list is not advertising, or anti-advertising any medicine or manufacturer, and is dictated by exclusively existing clinical and national recommendations for the use of antihistamines in pediatrics. The price range for specific dosages is for January. month of 2020, and is relevant for pharmacies of all forms of ownership on the territory of the Russian Federation.

Antihistamines for children from a year

Nomination a place Name of product price
Modern means of the second, or “third” generation 1 Ketotifen (Zaditen, Ketotifen Sofarma) 55 rub
2 Cetirizine (Zirtek Zodak-drops, Parlazin) 112 rub
3 Desloratadine (Erius, Blogir-3, Lordestine) 565 rub
4 Fenistil (dimetinden) 357 r
The first generation of antihistamines 1 Clemastine (Tavegil) 139 rub
2 Diphenhydramine 11 rub

Modern means of the second, or “third” generation

In order not to return to this topic, let’s say a few words about antihistamines “third”, and, moreover, hypothetical “fourth” generation. In fact, while there is only 2 generations, and the third generation will be officially created only when the first antihistamine appears cardiovascular free drug system and the liver.

Of course, if you use the means of the second generation wisely, indications in therapeutic dosages, and as short as possible courses, knowing in advance about the risks associated with a particular pathology liver or cardiovascular system in a particular patient and to monitor, then we can consider this treatment quite safe: whoever is warned is armed. But if you read in network of drugs from the group of antihistamines of the third, or, especially, the fourth generation, do not flatter yourself: such no medicine has been created yet. If you look a couple dozen similar sites, then you will see that on professional medical resources, these drugs remain as a second generations, and moving them to a higher rank is nothing but simple advertising tricks.

And now we go directly to these medicinal drugs, and the first of them is membrane stabilizing, under the name Ketotifen. Original remedy – Zadit, but in it is currently very difficult to find in Russian Federation.

Ketotifen (Zaditen, Ketotifen Sofarma)

Popularity Rating: 4.9

Ketotifen (Zaditen, Ketotifen Sofarma)

But there is a pretty high-quality generic, which Sopharma companies are produced in Bulgaria. This is the syrup that costs inexpensively, from 70 to 160 rubles., for a bottle of 100 ml. It is shown to taking in babies starting from the age of six months. It is well tolerated, and Ketotifen himself is a little away from other anti-allergic drugs of the second generation, due to pronounced membrane-stabilizing effect, this is his second action other than antihistamine. It also works by suppressing excessive activity of eosinophils, and preventing their migration in focus of inflammation. Ketotifen, except for bronchial asthma and bronchospasm, good in situations with acute and chronic urticaria, atopic dermatitis. It must be used with meals, in dosage of 0.0125 mg of Ketotifen per 1 kg of body weight of the baby twice per day. The required dose can easily be measured using special dispenser.

Advantages and disadvantages

The advantage of Ketotifen can be considered an effective warning. narrowing of the bronchi, and this is important in the treatment of bronchial asthma. is he reduces the need for glucocorticosteroid dosage in children and agents that expand the bronchi – bronchodilators. Minus ketotifen can be considered quite a long development of the effect. Maximum the benefits of taking ketotifen arise only after a month, therefore, this tool is an exception to the rule and is accepted it is quite long. Of course, the drug also has side effects. effects. It may be mild sedation, drowsiness, increased appetite or dry mouth. Also a drug contraindicated in babies who are under 6 months old, pregnant and lactating women.

There is another important point. If Ketotifen Treatment Started while taking asthma medications, you can’t abruptly cancel them, especially when it comes to glucocorticosteroid hormones. There is a risk of adrenal insufficiency. Is possible and an overdose of ketotifen, which in young children can proceed in the form of convulsive syndrome, lowering arterial pressure and drowsiness. Therefore, in no case should you exceed indicated dose.

Cetirizine (Zirtek Zodak-drops, Parlazin)

Popularity Rating: 4.8

Cetirizine (Zirtek Zodak-drops, Parlazin)

The next high-quality drug is Zirtek, but in drops produces its counterpart Hungarian company Egis, and it is called Parlazine, also a drug, is available in drops called Zodak-drops. It reliably protects from both early and late, or a delayed allergic reaction. In the bronchi decreases secretion, therefore breathing is easier, and the risk is reduced infection. It acts on histamine receptors, and in addition to antipruritic is believed to have pronounced antiexudative effect. Parlazin is shown in the case of allergic conjunctivitis and rhinitis, with hay fever, with Quincke’s edema, urticaria and various forms of itchy dermatoses. It is necessary to apply it to his kids from the age of 1 year to five drops, or 2.5 mg 2 times a day, and for children over the age of 2 years – 10 drops once. There is a parodyzin in the range from 230 to 300 rub for one bottle of 20 ml.

Advantages and disadvantages

No addiction develops to this medicine, and this means that the dose does not need to be increased, if required long reception. Still, after a long experience of use it turned out that the drug still causes a little drowsiness in children, it can also not be prescribed to pregnant and lactating women. But most likely, this is a commercial contraindication associated with insufficient research and good sales. However, if children have chronic renal failure, then the medicine should be used with extreme caution. May be side effects from taking Zirtek and Parlazin. It’s dry mouth as mentioned above, some drowsiness appears less often headache and dizziness, and with an overdose may be increased side effects, urinary retention appears, constipation and increased irritability.

Desloratadine (Erius, Blogir-3, Lordestine)

Popularity Rating: 4.7

Desloratadine (Erius, Blogir-3, Lordestine)

Erius is definitely one of the best reference drugs that It is produced, including in syrup, and can also be used in babies starting at 6 months of age. Erius is a remedy which in children’s allergology helps very well from various forms of skin itching, including from urticaria, successfully fights against allergic edema of the mucous membranes, even with smooth muscle spasm muscles.

It is important that the funds are never prescribed for prevention, but only to treat a condition that has already arisen. For example, stopping acute rhinorrhea with allergic rhinitis, itching in the eyes with allergic forms of conjunctivitis, or with severe skin itching, if there is urticaria. Toddlers from 1 year old and older, up to the age of five, you need to give 2.5 ml of syrup daily once a day. The medicine is taken inside out depending on the meal, and washed down with a small amount liquids.

In the form of syrup, Erius for babies is available in a dosage of 0.5 mg per 1 ml, in one bottle 60 ml, that is, the total dosage in the package 30 mg This syrup will cost from 420 to 680 rubles., Production well-known pharmaceutical company Schering-Plow. Exactly the same a syrup called Blogir-3 is produced by the Croatian company Belupo, and it will cost a little cheaper, from 300 to 430 rubles. at European quality.

Advantages and disadvantages

A big plus of Erius is the almost complete absence sedative effect, its good tolerance. Yet Erius can cause side effects, and most often it’s a headache, dry mouth, fatigue. Especially strong and there is no significant interaction with other drugs in Erius revealed, but due to the lack of clinical data, still not It is recommended to use it in pregnant and lactating women.

Fenistil (dimetinden)

Popularity Rating: 4.6

Fenistil

Fenistil is a very popular drug that is available in as a gel and as drops, and is indicated for use from the earliest age, and nowadays, it’s very “publicized”, on all television channels, and he has no analogues. His can be used even for babies, starting from a month old. Fenistil is a drug from the group of histamine receptors, and well tolerated, since pronounced anticholinergic dry mouth, dysuric disorders, There is practically no fenistil.

It is shown, except for food allergies, with hay fever, edema Quincke, insect bites, especially since it comes in the form of a gel, atopic dermatitis and chickenpox. For kids it is necessary to apply 2 drops per 1 kg of body weight per day, and divided into 3 doses. So, a baby weighing 9 kg per day will receive 18 drops, that is, 6 drops 3 times a day. Launches Fenistil Novartis Consumer Health, Switzerland, and a pack of 20 ml drops will cost 340 – 405 rub.

Advantages and disadvantages

Fenistil is perhaps the only histamine blocker, which can be used in babies from 1 month of age, this a very, very safe tool. However, if you get too carried away and an overdose occurs, then there may be tachycardia, expansion pupils and dry mouth, since anticholinergic effect with an overdose will still be pronounced, and especially in babies. Such an effect like urinary retention, and fever can give rise to false diagnosed with respiratory viral infections and neurological disorders. Of the contraindications to taking Fenistil necessarily should take into account bronchial asthma, which may be in children. Other contraindications apply to adults, for example, angle-closure glaucoma, or prostate adenoma, but a condition with bronchial asthma must be taken into account, as well as the presence of obstructive pulmonary disease.

The first generation of antihistamines

As mentioned above, drugs of the first generations are good at very short courses, for stopping suddenly arising and quite severe allergic conditions, and one of most effective drugs belonging to this the generation that is used in pediatrics is Tavegil (clemastine). Consider it carefully. Also do not go around the attention of diphenhydramine, which was mentioned above, and as regards other medicines of this generation, then their babies year-old can not be used yet. So, diazolin in tablets are indicated for use only from the age of five, and dragees Diazolin can be taken starting from 7 years. Very good antiallergic drug Fenkarol, but also him, despite the love of children’s allergists for this remedy should not be taken from children under three years of age, but after 3 years – please. AND although it does not cross the blood-brain barrier, it does not cause drowsiness, nevertheless, to parents of babies who are only only a year, it is better to refrain from taking it.

Clemastine (Tavegil)

Popularity Rating: 4.9

Clemastine (Tavegil)

It is the most effective and common antihistamine. 1st generation drug approved for use in children. Is acting long, sedation is not expressed due to the fact that the drug does not cross the blood-brain barrier. Tavegil also reduces vascular permeability, causes a mild situation, which is sometimes indicated for arousal in a child associated with itching, but it does not have sleeping pills.

Tavegil is produced by a large number of foreign companies in currently in the Russian Federation you can buy medicine made in Italy, for 20 tablets you will pay from 190 to 220 rubles. Indications for use of Tavegil are the same, starting from the contact dermatitis, urticaria, allergic rhinitis and conjunctivitis, and ending with insect bites and eczema.

Children need to give Tavegil only in syrup, aged from 1 year to six years – one teaspoon of syrup, one or two once a day at a dosage of 0.67 mg. A spoon is attached. Also Tavegil produced by pharmaceutical companies Nycomed, Sandoz, Takeda, and Hungarian company Egis. Such a large number of the best foreign manufacturers says that it really a good and high-quality drug, and even more interesting is that he has There are no generics at all, including those made in Russia.

Advantages and disadvantages

The merits of Tavegil were said above. It is used with success in pediatric practice, but it is contraindicated as once before the age of one year, and also it can not be assigned to babies, which there is a suspicion of bronchial asthma. Children from 1 year old Reception is shown only in the form of syrup. However, there may be side effects. effects such as excessive sedation, dizziness, lethargy. In children, quite often there may be the opposite side effect, which boils down to stimulating influence. It is irritability and anxiety, nervousness and manifestations of insomnia, in rare cases – a convulsive state. There may also be an overdose, which usually manifests itself. dry mouth, dilated pupils, and reddening of the upper half body.

Diphenhydramine

Popularity Rating: 4.8

Diphenhydramine

What good can be said about Diphenhydramine? First of all, he distributed everywhere, in the seediest village pharmacy it will be to be present, but, however, they will sell it to you only by prescription, despite all its cheapness. The cheapest diphenhydramine costs from 2 rub. 50 kopecks for 10 tablets! As an antihistamine, it is very good, especially if you need to call extra sleeping pills or sedation. However, the same “rudeness” of work at the same time is its side effect, since it penetrates well into the structures of the central nervous systems across the blood-brain barrier. Side effects are manifested by pronounced drowsiness, and with prolonged use it is dry skin, the development of constipation, the appearance of tachycardia.

How is diphenhydramine prescribed for children? It was said above that single dose for children up to 1 year – from 2 to 5 mg, and from 2 to 5 years the dose may be from 5 to 15 milligrams. However not on sale 5 mg tablets and tablets are available only 0.05 g, 10 times more than necessary. Yes, if they let out baby form, then it should not be tablets, but drops, or syrup. Therefore, all the same, it is advisable for parents not to use Diphenhydramine in children of the first year of life and older.

After all, parents themselves will not be able to choose correctly dosage and give it to the child, so here we are only talking about ambulance doctors who will put diphenhydramine in the baby need in the form of injections. Parents with him better not to contact.

The same can be said of such a popular drug as Suprastin. It is actively used in all allergic conditions. in children from 1 year and older, but only in the form of intramuscular injection, no syrup or solution for internal use not provided. And drugs in ampoules are administered only or by a doctor, or an ambulance paramedic, or at a medical facility with hospitalization, or day care.

Here are these few drugs and limited range of antihistamines which are shown to children aged 1 year to 3-4 years age.

Popularity rating based on analysis of demand data service wordstat.yandex.ru.


Attention! This rating is subjective, not advertising and does not serve as a guide to the purchase. Before the purchase consultation with a specialist is necessary.

Rate article
An online magazine about style, fashion, etiquette, lifestyle, and about choosing the best products and services.
Add a comment