10 modern pills and drugs for treatment kidney

Review of the best according to the editors. About the selection criteria. The the material is subjective, is not advertising and is not serves as a guide to the purchase. Before purchase is needed consultation with a specialist.

Many people without a medical education believe that everyone an organ in a person is treated only by its own special medicinal drugs. That’s right, because no one will give a laxative patient with edema, and diuretics for constipation. But it’s not so simple. Here are some examples. The inflammatory process is universal. This is a condition in which redness occurs, soreness, sensation of heat, swelling, and impaired function.

All these symptoms and signs can be well defined with the occurrence of acute, infectious arthritis with joint damage. The exact same pathological process associated with inflammation, can happen in any organ. Inflammation of the meninges – meningitis, brain – encephalitis, inflammation of the stomach – gastritis, and so on.

And for their treatment there is a large group of anti-inflammatory drugs to be shown almost always. In some cases where infection or viruses are to blame also antibacterial and antiviral agents, affecting the cause of the disease.

In addition to universal pathological processes, to “problems” You can look from the other side. For each organ, you can find many diseases that will be treated in the same way, and the same medicines as in other places. But there is for everyone organ and specific diseases that are treated by specific medicines. Today we will talk about kidney diseases, and about what are the special drugs that are are most often used in the pathology of this organ, which filters blood and forms urine.

From the anatomical and functional points of view of the kidney, urinary tract and genitals are combined into the urogenital the system. The kidneys are an organ that filters, cleanses the blood, forms urine, and the urinary system is the ureters, urinary bladder and urethra, their function is to accumulate and withdraw formed urine out.

In this drug review, we will only consider drugs which are used to treat kidney and urinary organs systems, and genital diseases, and specific medicines that are used, for example hormonal drugs will be considered in other reviews. All these funds are well known to urologists and nephrologists, that is, surgeons and therapists who treat patients with various kidney disease.

Of course, in one small article you cannot describe not only everything drugs, but even all their groups. therefore it was decided to consider a group of uroantiseptics that eliminate inflammation and proper treatment cleanse the urine of bacteria and make it sterile. The second group of drugs is a treatment nephrolithiasis, or urolithiasis. Despite the fact that human can be gallstone disease, the mechanism of education different kidney stones and gall bladder, stones are also obtained different, and you need to dissolve them using different medicinal preparations.

This material is informative, review character. The medicines indicated in it are chosen arbitrarily, but still the emphasis is on the most effective and popular funds that can be easily purchased in pharmacies of all forms property. For each drug, an INN is given, then There is an international nonproprietary name. If there’s the original drug, first launched on the market, then first in parentheses indicate the name of the original product, and then some generics, or commercial copies.

Then the price range for the most expensive and high-quality original drug, and the price of the cheapest medicines that can be bought at the pharmacy. Usually the most the cheap product does not have its commercial name, and called INN generic (generic). You can give an example. The non-steroidal anti-inflammatory drug meloxicam is an INN name. There can be many meloxicam, they are produced by various firms. It can be a Mirlox drug, it can be Melokan, Amelotex, Arthrosan, Genitron, and this may be Movalis. Wherein Movalis was first introduced to the market, and then other companies began to copy this funds when the manufacturing company took off patent for limitation.

The original drug, which is first introduced to the market, has the largest number of different studies spent on it most money and time, and it costs more. And here the cheapest drugs will not have their own name, and can be found Meloxicam Avexima, Meloxicam Akrikhin, and others preparations to which the name is added to the INN name manufacturing company.

Overview of pills and drugs for treating kidneys

Nomination a place Name of product price
Uroseptics 1 Nitroxoline (5-NOC) 160 rub
2 Furazidine (Furamag) 439 rub
3 Nitrofurantoin (Furadonin) 157 rub
4 Pipemidic acid (Palin) 172 rub
5 Nifurathel (Macmirror) 898 rub
Preparations for the treatment of ICD (nephrourolithiasis) 1 Blemaren (citric acid + potassium bicarbonate + sodium citrate) 1 054 rub.
2 Allopurinol 119 rub
3 Rovatinex 1 259 rub.
4 Urolesan 392 rub
5 Phytolysin 384 rub

Uroseptics

Let’s start a review of drugs for treating kidneys with very popular funds from the group of uroseptics. Uroseptics, or uroantiseptics, are medications that are taken in tablets, and their greatest concentration gradually accumulates in the urine. it very important property. To deliver medicine to any other organ, it is enough that they are actively absorbed from intestines, did not change in the liver, entered the bloodstream, and created there current concentration. Going through some organ for example, through the spleen, the medicine will do its job, because blood capillaries will deliver it to each cell of the spleen.

But the kidneys are a special organ. They only let blood through a certain moment, and then filter it, from the blood arises urine. So many drugs that can get into blood, do not pass into the urine, or create insufficient concentration. And so they treat diseases such as pyelonephritis, cystitis, pyelitis, urethritis, impossible. And here uroantiseptics do an excellent job of this. Another one an important feature – they do not have a systemic effect, that is, getting into urine, they destroy microbes, and on other organs they do not affect.

Uroseptics are used not only in acute processes, but also in chronic inflammatory lesions of the kidneys. They can be taken for many months, but always as prescribed by the doctor, and gradually eliminate along with antibiotics microbial inflammatory process. What uroantiseptics are used in our time?

Nitroxoline (5-NOC)

Popularity Rating: 4.9

Nitroxoline

Nitroxoline aka 5-NOC, orange tablets for treatment kidney, as patients say. Nitroxoline refers to synthetic antibacterial drugs, and has not only antimicrobial, but also antifungal effect, therefore, it is indicated for the treatment of urinary infections in conditions low immunity.

The drug, despite the fact that it has been used for a long time, affects most germs that cause infections urinary tract, both gram-positive and gram-negative Flora. E. coli highly sensitive to nitroxoline ureaplasma and mycoplasma, candidiasis pathogens. Not really sensitive to this drug are protein and staphylococcus, and in fact if a urinary tract infection is caused by Klebsiella, anaerobic flora or enterobacter, then this tool should not be used follows.

Thus, it is necessary to prescribe uroantiseptics only after identifying the corresponding pathogen, and determining it sensitivity to a particular antibiotic. It is shown a treatment for various inflammatory diseases, and it doesn’t matter – it’s a pathology of the kidneys or bladder, it’s important that microorganism cultures isolated from the patient were sensitive to nitroxoline. If the patient has impaired renal function and symptoms of renal failure, drug accumulation is possible in the body, and the appearance of the effect of accumulation, therefore, it is necessary be careful. 5-NOC should be used orally in medium a dose of 400 mg per day (2 tablets of 50 mg) four times a day. This is not very convenient, the reception is too frequent. With renal deficiency need to reduce the dose by half. Releases 5-NOC Lek company from Slovenia, and a pack of 50 tablets, which is enough for about a week, it will cost from 160 to 300 rubles.

Advantages and disadvantages

The advantage of nitroxoline will be high sensitivity to it. the most common pathogens of urinary infections, as well as antifungal activity. The drug may be prescribed during driving a car and in hazardous work, it does not affect ability to control mechanisms. Extremely rare to him an allergy develops such as a skin rash – no more than one case per thousand people. Perhaps the most uncomfortable moment you can count the frequent intake of a large number of tablets, 8 tablets per day. In some cases, the dosage may not be 400 mg per day, but 800, that is, you need to take 16 tablets daily nitroxoline, This is very inconvenient.

Furazidine (Furamag)

Popularity Rating: 4.8

FURAZIDIN

Furazidine, or Furamag, is a popular medicinal product. a tool that urologists love and prescribe it for a long term, including in children, in the presence of a vesicoureteral reflux, as well as reflux from the ureters to the renal pelvis. it remedy in brownish-yellow capsules, each of them contains 50 mg of furazidine. Unlike the previous medicine, he is the most effective against coccal flora, which has gram-positive characteristics are streptococci and staphylococci. E. coli are also sensitive Salmonella, Shigella, Enterobacter and Klebsiella.

Depending on the high and low concentration, he or stops the development of microorganisms, that is, has bacteriostatic effect, or destroys them, producing bactericidal effect. The medicine is prescribed for almost all urogenital acute and chronic infections, with gynecological infectious conditions, with infected burns of the skin and subcutaneous fiber.

It is very important that the drug can be used in a short course. as a means of prevention against invasive urological diagnostic procedures. This is cystoscopy, catheterization, and other surgical procedures. Furamag is sold in capsules at 50 mg, and adults need to take one capsule 3 times a day, or 2 capsules 3 times a day. Average course duration treatment – up to 10 days. As a prophylaxis before surgical by manipulations, the drug is prescribed one capsule 1 time in half an hour before the intervention.

The Furamag preparation is made by the Latvian company Onlinefarm, and one pack of 30 capsules, designed for 10 days, that is, as times per admission course, will cost retail from 560 to 950 rubles.

Advantages and disadvantages

The advantage of this drug is its slow development microbial resistance, as well as the ability to apply it to children over the age of three. The tool, unlike the previous one, still not so often taken, but it is advisable to drink it a lot of fluid. Of the side effects noted occasionally nausea, headache, and skin rash. You can’t take it a remedy for severe renal failure, with pregnancy and lactation, and children up to 3 years. Very important that against the background of taking Furamag and other nitrofurans is not necessary take medications that acidify urine. It reduce drug activity. Acidify urine, for example, ascorbic acid and calcium chloride.

Nitrofurantoin (Furadonin)

Popularity Rating: 4.7

Nitrofurantoin

Furadonin is quite old, and budget nitrofuran, and It is also inexpensive. These are ordinary tablets without any shell, or yellow, or yellow-green. Unlike the Furamag, it acts always bactericidal, that is, it destroys microbes regardless concentration. Its activity is high in the presence of gram-positive flora, streptococcus and staphylococcus, and gram-negative aerobes, Shigella and E. coli. It has almost no effect on mushrooms, and weak against enterococci. And if the patient has a protein, then it should not be prescribed furadonin.

Currently, this weak remedy is used for lung and uncomplicated forms of infectious processes in the form of cystitis or urethritis, and only if they were caused by sensitive to Furadonin is a microorganism. Just like in the case of Furamaga, its up still prescribed before urological interventions, but nevertheless, this tool cannot be considered modern and powerful. Furadonin is also used orally often, 4 times a day, one at a time or two tablets, i.e. 50 or 100 mg. In case of uncomplicated infection dosage should be 200 mg daily for weeks. The Latvian company Onlinefarm is releasing it, and one a package of 20 tablets will cost no more than 217 rubles.

Advantages and disadvantages

Furadonin has a pretty serious set contraindications – these are children under 6 years of age, the possibility the development of hemolytic anemia in the fetus as a consequence of taking pregnant, severe liver damage, chronic heart failure. Of the side effects, there is a risk of developing disorders peripheral nervous system, that is, polyneuropathy. In patients numbness in the extremities, crawling sensation may appear, and then the drug should be discontinued.

The medicine can cause hepatitis, hemolysis, and if used too long, fungal superinfection may occur, or insensitive or insensitive microorganisms. Doctors know that Furadonin should not be used in treatment of glomerulonephritis and prostatitis, for this there should be other drugs are prescribed. To top it off, a medicine can cause drowsiness and dizziness, and it is better not to control a car, and do not work in hazardous conditions labor during treatment.

This medicine has many side effects: and from gastrointestinal tract, and from the nervous and respiratory systems, and from the hematopoiesis. There may even be pains in joints, and the sudden onset of fever, coughing and chest pain. Therefore, if doctors seek to prescribe Furadonin, then it is worth asking them why this choice is justified. there is and more modern medicines.

Pipemidic acid (Palin)

Popularity Rating: 4.6

PIPEMIDIC ACID (PALINE)

Palin is a pretty good drug with Swiss quality, which is produced in Slovenia by Lek. The medicine is always bactericidal, and especially Palin is good if the patient gram negative flora. These are intestinal pathogenic sticks, enterobacter, proteus, gonococci, and from the positive flora – staphylococci. If the patient has an infection of the kidneys and urinary tract caused anaerobic flora, then this drug is better not assign. It can also be used not only for acute and chronic recurrent infections, but with the goal of prevention before surgical interventions in urology.

Tablets are available in a dosage of 200 mg, and are taken with after 12 hours, that is, one tablet in the morning, and one in the evening, always before eating. If the patient is isolated from staphylococcus urine, then add a third tablet so that in between There was no break for more than 8 hours. The course of taking the drug is about 10 days, but the doctor finally determines the duration. On the background it is advisable to take plenty of water to improve the passage urine. In pharmacies you can buy a package of Palina in an amount of 20 pieces for 10 days of admission, that is, the course will cost an average of 320 rubles. Domestic INN-generic, which produces the company Velfarm, then there is pipemidic acid, it will cost 140 rubles. for the same packaging.

Advantages and disadvantages

The advantage of the drug is a reasonable price, and enough rare reception. One tablet in the morning and one in the evening is already acceptable to modern man. However, the drug is necessary take long enough with prostatitis, up to 2 months. It is contraindicated in patients with epilepsy and with convulsive syndrome, prohibited for pregnant and lactating women, a remedy practically not used in pediatric practice. Minimum the age at which Palin can be prescribed is 14 years.

It has side effects – nausea and vomiting, mild skin itching If it is prescribed in the summer and at a high dose of 3 tablets per day, that may be photosensitivity, that is, the development of solar burns. If it is used too long, then microorganisms lose sensitivity to him. Special care is needed observe if this drug is prescribed to patients who have had or stroke, or transient ischemic attack.

Nifurathel (Macmirror)

Popularity Rating: 4.5

NIFUURATEL

The last drug from this group is an Italian remedy. Macmirror, or nifuratel, which is currently considered one of the best uroseptics. In addition to urinary tract infections, and gynecological diseases it is indicated in the complex treatment Helicobacter pylori infection, for the treatment of giardiasis and amoebic dysentery. Its activity against Helicobacter pylori infection allow it to be included in eradication schemes, and about such schemes described in detail in the corresponding article. The drug is active in against so many aerobic and anaerobic pathogens, and for diseases caused by protozoa.

Macmirror is indicated for the treatment of acute intestinal infections such as dysentery, salmonellosis, is highly active against fungi, and especially regarding candidiasis. If the patient has Helicobacter pylori infection, and metronidazole resistance, then Macmirror successfully replaces him in eradication schemes, about which The article says about the treatment of Helicobacter pylori infection. Medicine used for urinary tract infections at fairly high doses, on average 4-5 tablets per day for 1-2 weeks. The drug is produced in a package of 20 tablets, that is, one packaging for a patient with kidney and urinary tract infections is enough for 4 days. It costs one pack of makmiror from 850 to 1300 rubles. It is made in Italy, the company Doppel Pharma.

Advantages and disadvantages

MacMyror’s biggest flaw is its high price, and also the need to take it “handfuls”, but the multiplicity admission only twice a day, morning and evening. The drug has very high efficiency, wide spectrum of action, and toxicity and the degree of development of side effects in case of an overdose is very low. It is not used during pregnancy and lactation, but in due to the fact that no relevant studies have been conducted. Of side effects occurred only nausea, bitterness in the mouth, discomfort, itching and skin rash. The drug has no such contraindications, like other drugs from the group uroseptics, it can be used even with renal failure and chronic liver diseases, but very carefully, and under control analyzes. Therefore, if the doctor recommend uroantiseptics, then one of the modern and best drugs is Macmirror, and in this sense it can be considered complete the opposite of the old and rude Furadonin.

Preparations for the treatment of ICD (nephrourolithiasis)

Nephrolithiasis, or urolithiasis, is almost always at the beginning treated conservatively, that is, without surgery. The exception is the stone is too large and traumatic to the mucosa, causing bleeding, a coral stone that cannot be dissolved, as well as infected calculi. In all other cases special drugs are used that can induce medicinal litholysis, i.e. the destruction of stones by chemical way by changing the acidity of the urine. Since there are stones different, in some cases it is necessary to acidify urine, sometimes use drugs that inhibit special purine metabolism enzymes. And in some cases you need to alkalize urine. So, if the patient’s stones are composed of phosphates and oxalates calcium, then medicines containing magnesium help, as well as a remedy Xidiphone, which slows the release of calcium from bone tissue. Consider the most popular drugs that designed to treat urolithiasis.

Blemaren (citric acid + potassium bicarbonate + sodium citrate)

Popularity Rating: 4.9

Blemaren (citric acid + potassium hydrogen carbonate + sodium citrate)

Blemaren is a popular drug with a long history. Can say it is dry effervescent lemonade in tablets as it contains sodium citrate, citric acid and potassium bicarbonate. All it can alkalize urine and dissolve urinary stones. Mixed uric acid stones mixed uro-oxalate stones, cystine stones. Blemaren may also prevent the formation of mixed calcium-oxalate stones, but for this, the patient must make some efforts.

To treat urolithiasis, it’s not enough to just take pill and forget. Need to control how much has changed acid-base state of urine, and regularly measure it with test paper before taking medication. Blemaren occurs after the tablet is dissolved in a glass of water, it may to be fruit juice, tea, alkaline mineral water. Usually daily the dose is from 2 to 6 tablets, and after the start of treatment it is necessary to reach a specific pH of urine. Stones from uric acid dissolve in the range of 7.0-7.2, slightly wider pH range should be for dissolving urea-oxalate stones origin, from 6.8 to 7.4. If there are cystine stones, what it happens much less often, the urine pH range should be 7.5-8.5, then eat more alkaline.

The duration of treatment is long, and no less than 4-6 months. In some Blemaren cases are used to prevent stone formation, for example, during treatment with cytostatics. Produces Blemaren German company Esparma, and one pack of 80 effervescent tablets costs an average of 1250 rubles. With an average dosage of this amount enough for an average of half a month, so the cost of a monthly course about 2500 rub.

Advantages and disadvantages

The advantage of Blemaren is the ability to use it with different types of stones, creating a particular concentration of ions hydrogen (pH) in the urine. The disadvantage is the need for active patient participation in this process and daily, three-fold urine measurement. In order to achieve a confident concentration Blemaren without failures, that is, without sharp reductions, is necessary special skill, therefore, the correct, confident use of the product can only begin after a few days, when the patient himself titrates the dose. Blemaren, on the other hand, is a remedy that changes acid-base indicators, alkalizes the body. Therefore, it is contraindicated in renal failure, with alkalosis, and other serious disorders of electrolyte balance and acid – base balance.

Allopurinol

Popularity Rating: 4.8

ALLOPURINOL

Allopurinol is a drug that is used to reduce the concentration of uric acid in blood plasma, and apply it to long-term treatment of hyperuricemia. However, if the patient is diagnosed with urinary stones, which consist of urates, i.e. from uric acid salts, the drug is also indicated for treatment of this type of urolithiasis. Since urate stones are quite rare, in about 5% of all stones, then this infrequently prescribed drug. It is necessary to apply it only one once a day, and the average dosage is from 100 to 300 mg. If the daily dose will exceed 300 mg, then you need to break it into several receptions, for this small tablets are purchased dosage (100 mg). The average dose should be from 2 to 10 mg per kilogram of body weight per day. Allopurinol is available or domestic producer Organic, or Hungarian Aegis manufacturer. In the latter case, the cost of one package allopurinol from 30 tablets of 300 mg will not exceed 140 rub.

Advantages and disadvantages

Strictly speaking, allopurinol is not a direct drug for treatment of urolithiasis, but it can be considered a medicine preventive focus. His task is to make sure that concentration of urates, i.e. uric acid salts in blood plasma was low. This will prevent the appearance of new stones, and in to some extent, old stones can dissolve. But still the main way to prevent and treat urate calculus is a lifelong diet.

Rovatinex

Popularity Rating: 4.7

ROVATINEKS

This tool can be considered a dietary supplement with pronounced litholytic action. These are gelatin capsules that have strong, specific smell. The drug contains various plant compounds such as terpenes. The medicine increases diuresis, reduces spasms of smooth muscles, and promotes dissolution of stones due to the content of plant terpenes. Soluble terpenes, getting into the urine, dissolve stones that composed of calcium salts. But it is calcium stones that are the main way, and are found in various forms of nephrolithiasis. If the patient there are small stones, or sand, then antispasmodic the effect of Rovatinex allows you to slightly expand the ureters, improve renal blood flow, and facilitate self-passage stones. In this case, the kidney does not swell, and the blood flow in it is practically not is changing. Additionally, this agent has antimicrobial action.

Rovatinex is indicated both for the treatment of urolithiasis and for prevention. Use capsules before meals, one or two capsules three times a day, with renal colic, the dose rises several times, up to a maximum of 15 capsules per day. Releases Rovatineks Irish company, RovaFarm, and a package of 50 capsules, soluble in the intestine, will cost from 1000 to 2000 rubles. in a pharmacy.

Advantages and disadvantages

The disadvantage of this tool is its successful activity. only in the presence of calcium stones. If the patient has stones cystine, phosphate, or urate, this drug is not for him will do. Also, the drug is contraindicated in patients receiving oral anticoagulants, e.g. warfarin, for prophylaxis cardioembolic strokes. Rovatinex should not be taken if renal colic is too common if accompanied severe infection of the urinary tract.

Urolesan

Popularity Rating: 4.6

UROLESAN

Urolesan is perhaps the only drug for treatment urolithiasis, which is also still indicated for dissolution gallstones. However, it is sold in drops. His place in classification is a myotropic antispasmodic, that is, a drug, relaxing smooth muscles. It consists of castor, fir and peppermint oil, from extracts of hops, oregano and carrots. As a result these plant components increase urine output, acidify it, along the way, increase the formation of bile, have a disinfectant properties. In addition to urolithiasis and gallstone disease, Urolesan indicated for pyelonephritis, cholecystitis and cholangiohepatitis.

It is prescribed before meals, it is necessary to drip 10 drops per piece of sugar and suck it under the tongue. So it is necessary to do three times a day. The average duration of treatment is from 1 week to 1 month, and if the patient has renal and hepatic colic, then a single dose may be doubled. Ukrainian company launches Urolesan halichfarm, and there is a rather big difference between the road and cheap packaging. A bottle containing 25 ml drops, at retail may cost from 260 to 520 rubles, that is, the price fluctuates with a large scatter.

Advantages and disadvantages

The advantage of Urolesan is that it acts softly, practically has no side effects, except for slight dizziness, nausea, and even with individual intolerance. But this the product is not a drug that is directly indicated for dissolving urinary stones. He acidifies urine, and against his background other professional drugs may be prescribed. On the background of the reception Urolesana conduct dynamic observation, preparing the patient for remote lithotripsy to facilitate stone discharge (antispasmodic effect). Contraindications almost none but individual intolerance and too large size stones in the kidneys, as well as gastric ulcer, gastritis with high acidity, and childhood.

Phytolysin

Popularity Rating: 4.5

Fitolizin

Finally, a widely used drug containing phytoextracts, with nephrolithiasis, can be considered Phytolysin, which used in the treatment of urolithiasis. Phytolysin – it is a paste preparation that contains many plant ingredients. This is goldenrod and horsetail, bird highlander and wheat grass, onion husk and leaves of birch, parsley and lovage root, seeds fenugreek, and four vegetable oils: peppermint, sage, and pine an orange. Such an exquisite combination leads to relaxation. smooth muscles of the ureters, stimulation of diuresis, help in dissolving small stones.

The best effect of phytolysin in those patients who have medium-sized stones, and sand. It promotes leaching of sand and small pebbles from the kidneys. Phytolysin reduces potential crystallization ability of urine. Fitolizin should be used according to one teaspoon inward, three times a day, dissolved in half glasses of water. The average duration of treatment is 3-4 weeks. You can buy Phytolysin at a price of 350 to 620 rubles, per 100 g paste. It is released by the Polish company Herbopol-Polfa.

Advantages and disadvantages

This drug can be used, as well as the previous one (Urolesan), in complex therapy, with exacerbations of inflammatory lesions kidney and urolithiasis. Then he needs a cover in the form antiseptics, antibiotics, more serious drugs for dissolving stones. When a patient begins remission, and exacerbation decays, then you can leave only Fitolizin so that it worked with urine sand. The drug is well tolerated, but it has There are contraindications for use. In addition to individual intolerance, it’s kidney and heart failure, various types of glomerulonephritis, as well as urinary stones containing phosphate. It is contraindicated in children, pregnant and lactating women. Of side effects most often occurs nausea and skin allergic reactions.

Popularity rating based on analysis of demand data service wordstat.yandex.ru.


Attention! This rating is subjective, not advertising and does not serve as a guide to the purchase. Before the purchase consultation with a specialist is necessary.

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